>hPTPsigma_D1_(NP_002841)_PTPRS .
ADMAEHTERLKANDS------LKLSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVILQPIEGI---------------------MGSDYINANYVDGYRRQN-
-------AYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEK-SRIKCDQYWPN----
RGTETYGFIQVTL-LDTIE-LATFCVRTFSLHKNGSSEKRE-----------VRQFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPIVVHCSAGVGRTGCF
IVIDAMLERIKP---EKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVG
>mPTPsigma_D1_(NP_035348(revised))_Ptprs .
TDMAEHMERLKANDS------LKLSQEYESIDPG----QQFTWEH---SNLEANKPK-NR
YANVIAYDHSRVILQPLEGI---------------------MGSDYINANYVDGYRRQN-
-------AYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEK-SRIKCDQYWPN----
RGTETYGFIQVTL-LDTME-LATFCVRTFSLHKNGSSEKRE-----------VRHFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPIVVHCSAGVGRTGCF
IVIDAMLERIKT---EKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVG
>rPTPsigma_D1_(NP_062013)_Ptprd .
TDMAEHMERLKANDS------LKLSQEYESIDPG----QQFTWEH---SNLEANKPK-NR
YANVIAYDHSRVILQPLEGI---------------------MGSDYINANYVDGYRRQN-
-------AYIATQGPLPETFGDFWRMVWEQRSATVVMMTRLEEK-SRVKCDQYWPN----
RGTETYGFIQVTL-LDTME-LATFCVRTFSLHKNGSSEKRE-----------VRHFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPVVVHCSAGVGRTGCF
IVIDAMLERIRT---EKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVG
>cPTPsigma_D1_(I50212) .
SELAEHTEHLKANDN------LKLSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVILLPIEGI---------------------VGSDYINANYIDGYRKQN-
-------AYIATQGPLPETFGDFWRMVWEQRSATIVMMTKLEEK-SRIKCDQYWPG----
RGTDTYGMIQVTL-LDTIE-LATFCVRTFSLHKNGSSEKRE-----------VRQFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPIVVHCSAGVGRTGCF
IVIDAMLERIKH---EKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVA
>xPTPsigma_D1_(AAF43607) .
ADLAEHTEHLKANDN------LKLSQEYESVDPG----QQFTWEH---SNLEVNKAK-NR
YANVIAYDHSRVILLPVEGI---------------------IGSDYINANYIDGYRKQN-
-------AYIATQGALPETFGDFWRMVWEQRSATVVMMTKLEEK-SRVKCDQYWPS----
RGTETYGMIQVTL-LDTIE-LATFCVRTFSLHKSGSSEKRE-----------VRQFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPIVVHCSAGVGRTGCF
IVIDAMLERIKH---EKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVA
>zPTPsigma_D1_(CAC44759) .
SELAEHTELLKANDN------LKLSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVILAPIEGI---------------------TGSDYINSNYIDGYRKQN-
-------AYIATQGPLPETFGDFWRMVWEQRAATVVMMTRLEEK-SRIKCDQYWPS----
RGTETYGMIQVTL-LDTIE-LATFCVRTFSLHKNGSSEKRE-----------VRQFQFTA
WPDHGVPEY--PTPFLAFLRRVKTCN-------------PPDAGPIIAHCSAGVGRTGCF
IVIDAMLERIKH---EKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVA
>hLAR_D1_(NP_002831)_PTPRF .
TDLADNIERLKANDG------LKFSQEYESIDPG----QQFTWEN---SNLEVNKPK-NR
YANVIAYDHSRVILTSIDGV---------------------PGSDYINANYIDGYRKQN-
-------AYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEK-SRVKCDQYWPA----
RGTETCGLIQVTL-LDTVE-LATYTVRTFALHKSGSSEKRE-----------LRQFQFMA
WPDHGVPEY--PTPILAFLRRVKACN-------------PLDAGPMVVHCSAGVGRTGCF
IVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT
>mLAR_D1_(NP_035343)_Ptprf .
TDLADNIERLKANDG------LKFSQEYESIDPG----QQFTWEN---SNSEVNKPK-NR
YADVIAYDHSRVLLTSIDGV---------------------PGSDYINANYIDGYRKQN-
-------AYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEK-SRVKCDQYWPV----
RGTETYGLIQVTL-VDTVE-LATYTMRTFALHKSGSSEKRE-----------LRQFQFMA
WPDHGVPEY--PTPILAFLRRVKACN-------------PLDAGPMVVHCSAGVGRTGCF
IVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAM
>rLAR_D1_(NP_062122)_Ptprf .
TDLADNIERLKANDG------LKFSQEYESIDPG----QQFTWEN---SNSEVNKPK-NR
YANVIAYDHSRVLLTSIDGV---------------------PGSDYINANYIDGYRKQN-
-------AYIATQGPLPETMGDFWRMVWEQRIATVVMMTRLEEK-SRVKCDQYWPA----
RGTETYGLIQVTL-VDTVE-LATYTMRTFALHKSGSSEKRE-----------LRQFQFMA
WPDHGVPEY--PTPILAFLRRVKACN-------------PLDAGPMVVHCSAGVGRTGCF
IVIDAMLERMKH---EKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAM
>xLAR_D1_(AAF43606) .
SDLADNIERLKANDG------LKFSQEYESIDPG----QQFTWEN---SNLEVNKPK-NR
YANVIAYDHSRVILTSVDAV---------------------PGSDYINANYIDGYRKQN-
-------AYIATQGPLPETITDFWRMMWEQRTATIVMMTRLEEK-SRVKCDQYWPS----
RGSETYGMIQVTL-MDTVE-LATYTVRTFTVYKNGSNEKRD-----------VRQFQFMA
WPDHGVPEY--PTPILGFLRRVKACN-------------PPDAGPMFVHCSAGVGRTGCF
IVIDAMLERVKL---EKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAVM
>hPTPdelta__D1_(NP_002830)_PTPRD .
LELADHIERLKANDN------LKFSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVLLSAIEGI---------------------PGSDYVNANYIDGYRKQN-
-------AYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEER-SRVKCDQYWPS----
RGTETHGLVQVTL-LDTVE-LATYCVRTFALYKNGSSEKRE-----------VRQFQFTA
WPDHGVPEH--PTPFLAFLRRVKTCN-------------PPDAGPMVVHCSAGVGRTGCF
IVIDAMLERIKH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVT
>mPTPdelta_D1_(D54689) .
LELADHIERLKANDN------LKFSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVLLSAIEGI---------------------PGSDYVNANYIDGYRKQN-
-------AYIATQGSLPETFGDFWRMIWEQ-EATVVMMTKLEER-SRVKCDQYWPS----
RGTETHGLVQVTL-LDTVE-LT-YCVRTFALYNNGSSEKRK-----------VRQFQFTA
WPDHGVPEH--PTPFLAFLRRVKTCN-------------PPDAGPMVVHCSAGVGRTGCF
IVIDAMLERIKH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVT
>xPTPdelta_D1_(AAF43605) .
LELEDHIERLKANDN------LKFSQEYESIDPG----QQFTWEH---SNLEVNKPK-NR
YANVIAYDHSRVLLSAIDGI---------------------PGSDYINSNYIDGYRKQN-
-------AYIATQGPLPETFGDFWRMMWEQRSATVVMMTKMEER-SRIKCDQYWPS----
RGTETYGLIQVTL-LDTVE-LATYTVRTFALYKNGSSEKRE-----------VRQFQFTA
WPDHGVPEH--PTPFLAFLRRVKTCN-------------PPDAGPMVVHCSAGVGRTGCF
NVIDAMLERIRH---EKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVT
>hPTPrho_D1_(NP_573400)_PTPRT .
ADLLQHITQMKRGQG------YGFKEEYEALPEG----QTASWDT---AKEDENRNK-NR
YGNIISYDHSRVRLLVLDGD---------------------PHSDYINANYIDGYHRPR-
-------HYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEV-GRVKCVRYWPD----
-DTEVYGDIKVTL-IETEP-LAEYVIRTFTVQKKGYHEIRE-----------LRLFHFTS
WPDHGVPCY--ATGLLGFVRQVKFLN-------------PPEAGPIVVHCSAGAGRTGCF
IAIDTMLDMAEN---EGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACL
>mPTPrho_D1_(NP_067439)_Ptprt .
ADLLQHITQMKRGQG------YGFKEEYEALPEG----QTASWDT---AKEDENRNK-NR
YGNIISYDHSRVRLLVLDGD---------------------PHSDYINANYIDGYHRPR-
-------HYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEV-GRVKCVRYWPD----
-DTEVYGDIKVTL-IETEP-LAEYVIRTFTVQKKGYHEIRE-----------LRLFHFTS
WPDHGVPCY--ATGLLGFVRQVKFLN-------------PPEAGPIVVHCSAGAGRTGCF
IAIDTMLDMAEN---EGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACL
>xPTPrho_D1_(AAD50295) .
ADLLQHITQMKRGQG------YGFKEEYEALPEG----QTASWDT---AKEDENRNK-NR
YGNIISYDHSRVRLQQIEED---------------------PHSDYINANYVDGYHRPR-
-------YYIATQGPMQETVKDFWRMIWQENSISVVMVTNLVEV-GRVKCVRYWPD----
-DTEVYGDIKVSA-IETEP-LAEYIIRTFTVQKKGSHEIRE-----------IRQFHFTS
WPDNGVPCY--ATGLLGFIRQVKFLN-------------PPDAGPITVHCSAGAGRTGCF
IAIDIMLDMAEN---EGVVDIFNCVRELRAQRVNMVQTEEQYVFVHDAILEACL
>hPTPmu_D1_(NP_002836)_PTPRM .
ADLLQHITQMKCAEG------YGFKEEYESFFEG----QSAPWDS---AKKDENRMK-NR
YGNIIAYDHSRVRLQTIEGD---------------------TNSDYINGNYIDGYHRPN-
-------HYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEV-GRVKCCKYWPD----
-DTEIYKDIKVTL-IETEL-LAEYVIRTFAVEKRGVHEIRE-----------IRQFHFTG
WPDHGVPYH--ATGLLGFVRQVKSKS-------------PPSAGPLVVHCSAGAGRTGCF
IVIDIMLDMAER---EGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACL
>mPTPmu_D1_(NP_033010)_Ptprm .
ADLLQHITQMKCAEG------YGFKEEYESFFEG----QSAPWDS---AKKDENRMK-NR
YGNIIAYDHSRVRLQMLEGD---------------------NNSDYINGNYIDGYHRPN-
-------HYIATQGPMQETIYDFWRMVWHENTASIIMVTNLVEV-GRVKCCKYWPD----
-DTEIYKDIKVTL-IDTEL-LAEYVIRTFAVEKRGIHEIRE-----------IRQFHFTG
WPDHGVPYH--ATGLLGFVRQVKSKS-------------PPNAGPLVVHCSAGAGRTGCF
IVIDIMLDMAER---EGVVDIYNCVRELRSRRVNMVQTEEQYVFIHDAILEACL
>hPTPkappa_D1_(NP_002835)_PTPRK .
ADLLQHINLMKTSDS------YGFKEEYESFFEG----QSASWDV---AKKDQNRAK-NR
YGNIIAYDHSRVILQPVEDD---------------------PSSDYINANYIDGYQRPS-
-------HYIATQGPVHETVYDFWRMIWQEQSACIVMVTNLVEV-GRVKCYKYWPD----
-DTEVYGDFKVTC-VEMEP-LAEYVVRTFTLERRGYNEIRE-----------VKQFHFTG
WPDHGVPYH--ATGLLSFIRRVKLSN-------------PPSAGPIVVHCSAGAGRTGCY
IVIDIMLDMAER---EGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACL
>mPTPkappa_D1_(NP_033009_(revised))_Ptprk .
ADLLQHINLMKTSDS------YGFKEEYESFFEG----QSASWDV---AKKDQNRAK-NR
YGNIIAYDHSRVILQPVEDD---------------------PSSDYINANYRDGYQRPS-
-------HYIATQGPVHETVYDFWRMVWQEQSACIVMVTNLVEV-GRVKCYKYWPD----
-DTEVYGDFKVTC-VEMEP-LAEYVVRTFTLERRGYNEIRE-----------VKQFHFTG
WPDHGVPYH--ATGLLSFIRRVKLSN-------------PPSAGPIVVHCSAGAGRTGCY
IVIDIMLDMAER---EGVVDIYNCVKALRSRRINMVQTEEQYIFIHDAILEACL
>hPTPlamda_D1_(NP_005695)_PTPRU .
ADLLQHINQMKTAEG------YGFKQEYESFFEG--------WD----ATKKKDKVKGSR
QEPMPAYDRHRVKLHPMLGD---------------------PNADYINANYIDGYHRSN-
-------HFIATQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEV-GRVKCSRYWPE----
-DSDTYGDIKIML-VKTET-LAEYVVRTFALERRGYSARHE-----------VRQFHFTA
WPEHGVPYH--ATGLLAFIRRVKAST-------------PPDAGPIVIHCSAGTGRTGCY
IVLDVMLDMAEC---EGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACL
>mPTPlamda_D1_(NP_035344)_Ptprl .
ADLLQHINQMKTAEG------YGFKQEYESFFEG--------WD----ATKKKDKLKGGR
QEPVSAYDRHHVKLHPMLAD---------------------PDADYISANYIDGYHRSN-
-------HFIATQGPKPEMIYDFWRMVWQEQCASIVMITKLVEV-GRVKCSRYWPE----
-DSDMYGDIKITL-VKTET-LAEYVVRTFALERRGYSARHE-----------VRQFHFTA
WPEHGVPYH--ATGLLAFIRRVKAST-------------PPDAGPIVIHCSAGTGRTGCY
IVLDVMLDMAEC---EGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILEACL
>rPTPpsi_D1_(AAB42210)_Ptpru_Fragm .
ADLLQHINQMKTAEG------YGFKQEYESFFEG--------WD----ATKKKDKLKSGR
QEPVSAYDRHRVKLHPMLGD---------------------PDADYISANYIDGYHRPN-
-------HFIATQGPKPEMIYDFWRMVWQEQCVSVVMISKLVEV-GRVKCSRYWPE----
-HSDMYGDIKITL-VKTET-LAEYVVRTFALERRGYSARHE-----------VRQFHFTA
WPEHGVPYH--ATGLLAFIRRVKAST-------------PPDAGPVVIHCSAGTGRTGCY
IVLDVMLDMAEC---EGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE---
>cPTPalpha_D1_(AAB04150) .
DKLEEEINRRIGDDN------KLFREEFNALP------ACPIQATCEAASKEENKEK-NR
YVNILPYDHSRVHLTPVEGV---------------------PDSHYINTSFINSYQEKN-
-------KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWTYGNIRVSV-EDVTV-LVDYTVRKFCIQQVGDVTNKKPQ-------RLVTQFHFTS
WPDFGVPFT--PIGMLKFLKKVKTCN-------------PQYAGAIVVHCSAGVGRTGTF
IVIDAMLDMMHA---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL
>hPTPalpha_D1_(NP_002827)_PTPRA .
DKLEEEINRRMADDN------KLFREEFNALP------ACPIQATCEAASKEENKEK-NR
YVNILPYDHSRVHLTPVEGV---------------------PDSDYINASFINGYQEKN-
-------KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWTYGNIRVSV-EDVTV-LVDYTVRKFCIQQVGDMTNRKPQ-------RLITQFHFTS
WPDFGVPFT--PIGMLKFLKKVKACN-------------PQYAGAIVVHCSAGVGRTGTF
VVIDAMLDMMHT---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL
>mPTPalpha_D1_(AAK56109)_Ptpra .
DKLEEEINRRMADDN------KLFREEFNALP------ACPIQATCEAASKEENKEK-NR
YVNILPYDHSRVHLTPVEGV---------------------PDSDYINASFINGYQEKN-
-------KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWTYGNVRVSV-EDVTV-LVDYTVRKFCIQQVGDVTNRKPQ-------RLITQFHFTS
WPDFGVPFT--PIGMLKFLKKVKACN-------------PQYAGAIVVHCSAGVGRTGTF
VVIDAMLDMMHS---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL
>rPTPalpha_D1_(NP_036895)_Ptpra .
DKLEEEINRRMADDN------KLFREEFNALP------ACPIQATCEAASKEENKEK-NR
YVNLLPYDHSRVHLTPVEGV---------------------PDSDYINASFINGYQEKN-
-------KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWPYGNVRVSV-EDVTV-LVDYTVRKFCIQQVGDVTNRKPQ-------RLITQFHFTS
WPDFGVPFT--PIGMLKFLKKVKACN-------------PQYAGAIVVHCSAGVGRTGTF
VVIDAMLDMMHS---ERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL
>zPTPalpha_D1_(NP_571963)_ptpra .
DKLEEEMNRRMADDN------KLFREEFNALP------VCPIQASCDAASKEESKEK-NR
YVNILPYDHSRVHLTSLEGV---------------------PDSDYINASYINGYQEKN-
-------KFIAAQGPKEETVNDYWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWTYGNIRVSV-EDTMI-LVDYTIRKFCIQQVGDVSGKKPQ-------RLVTQFHFTS
WPDFGVPFT--PIGMLKFLKKVKNCN-------------PQYAGPIVVHCSAGVGRTGTF
IVIDAMLDMMGA---ERKVDVFGFVTRIRAQRCQMVQTDMQYVFIFQALLEHYL
>xPTPalpha_D1_(AAA17990) .
DKLEEEINRRMADDN------KLFREESNALP------ACPIQATCEAASKEENMEK-NR
YVNILPYDHSRVHLSPIEGV---------------------PDSDYINSSFINGYQEKN-
-------KFIAAQGPKEETVNDFWRMIWEQNTATIVMVTNLKER-KECKCAQYWPD----
QGCWTYGNIRVSV-EDMTV-LVDYTVRKFCIQQVGDVTNKKPQ-------RLITQFHFTS
WPDFGVPFT--PIGMLKFLKKVKNCN-------------PQYAGAIVVHCSAGVGRTGTF
MVIDAMLDMMNT---EKKVDVYGFVTRIRAQRCQMVQTDMQYVFIYQALLEHFL
>hPTPepsilon_D1_(NP_006495)_PTPRE .
EHLEEEIRIRSADDC------KQFREEFNSLP------SGHIQGTFELANKEENREK-NR
YPNILPNDHSRVILSQLDGI---------------------PCSDYINASYIDGYKEKN-
-------KFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKER-KEEKCHQYWPD----
QGCWTYGNIRVCV-EDCVV-LVDYTIRKFCIQPQLPDGCKAP--------RLVSQLHFTS
WPDFGVPFT--PIGMLKFLKKVKTLN-------------PVHAGPIVVHCSAGVGRTGTF
IVIDAMMAMMHA---EQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYL
>mPTPepsilon_D1_(NP_035342)_Ptpre .
EHLEEEIRVRSADDC------KRFREEFNSLP------SGHIQGTFELANKEENREK-NR
YPNILPNDHCRVILSQVDGI---------------------PCSDYINASYIDGYKEKN-
-------KFIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKER-KEEKCYQYWPD----
QGCWTYGNIRVCV-EDCVV-LVDYTIRKFCIHPQLPDSCKAP--------RLVSQLHFTS
WPDFGVPFT--PIGMLKFLKKVKTLN-------------PSHAGPIVVHCSAGVGRTGTF
IVIDAMMDMIHS---EQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYL
>rPTPepsilon_D1_(XP_215102)_Ptpre .
EHLEEEIRVRSADDC------KRFREEFNSLP------SGHIQGTFELANKEENREK-NR
YPNILPNDHCRVILSQLDGI---------------------PCSDYINASYIDGYKEKN-
-------KFIAAQGPKQETVNDFWRMVWEQRSATIVMLTNLKER-KEEKCYQYWPD----
QGCWTYGNIRVCV-EDCVV-LVDYTIRKFCIHPQLPDSCKAP--------RLVSQLHFTS
WPDFGVPFT--PIGMLKFLKKVKTLN-------------PSHAGPIVVHCSAGVGRTGTF
IVIDAMMDMIHS---EQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYL
>hPTPgamma_D1_(NP_002832)_PTPRG .
KQFVKHIGELYSNNQ------HGFSEDFEEVQRC----TADMNITAEHSNHPENKHK-NR
YINILAYDHSRVKLRPLPGKDS-------------------KHSDYINANYVDGYNKAK-
-------AYIATQGPLKSTFEDFWRMIWEQNTGIIVMITNLVEK-GRRKCDQYWPT----
ENSEEYGNIIVTL-KSTKI-HACYTVRRFSIRNTKVKKGQKGNPKGRQNERVVIQYHYTQ
WPDMGVPEY--ALPVLTFVRRSSAAR-------------MPETGPVLVHCSAGVGRTGTY
IVIDSMLQQIKD---KSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAIL
>mPTPgamma_D1_(NP_033007)_Ptprg .
KQFGKHIGELYSNSQ------HGFSEDFEEVQRC----TADMNITAEHSNHPDNKHK-NR
YINILAYDHSRVKLRPLPGKDS-------------------KHSDYINANYVDGYNKAK-
-------AYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEK-GRRKCDQYWPT----
ENTEEYGNIIVTL-KSTKV-HACYTVRRLSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQ
WPDMGVPEY--ALPVLTFVRRSSAAR-------------MPDMGPVLVHCSAGVGRTGTY
IVIDSMLQQIKD---KSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAIL
>rPTPgamma__D1_(NP_599183)_Ptprg .
IPIPDDMEAIPVKQF--GKSQHGFSGDFEEVQRC----TADMNITAEHSNHPDNKHK-NR
YINILAYDHSRVKLRPLPGKDS-------------------KHSDYINANYVDGYNKAK-
-------AYIATQGPLKSTFEDFWRMIWEQNTGIIIMITNLVEK-GRRKCDQYWPT----
ENTEEYGNIIVTL-KSTEV-HACYTVRRFSVRNTKVKKGQKGNPKGRQNERTVIQYHYTQ
WPDMGVPEY--ALPVLTFVRRSSAAR-------------MPDMGPVLVHCSAGVGRTGTY
IVIDSMLQQIKD---KSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAIL
>cPTPgamma_D1_(Q98936) .
KQFVKHISELYSNNQ------HGFSEDFEEVQRC----TADMNITAEHSNHPDNKHK-NR
YINILAYDHSRVKLRPLPGKDS-------------------KHSDYINANYVSGYNKAK-
-------AYIATQGPLKSTFEDFWRMIWAQHTGIIVMITNLVEK-GRRKCDQYWPT----
ENSEEYGNIIVTL-KSTNI-HACYTVRPLHGQEHKDEKGSERKPKGRQNERTVIQYHYTQ
WPDMGVPEY--ALPVLTFVRRSSAAR-------------TPHMGPVVVHCSAGVGRTGTY
IVIDSMLQQIKD---KSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAIL
>hPTPzeta_D1_(NP_002842)_PTPRZ1 .
KHFPKHVADLHASSG-FTEEFETLKEFYQEVQSC----TVDLGITADSSNHPDNKHK-NR
YINIVAYDHSRVKLAQLAEKDG-------------------KLTDYINANYVDGYNRPK-
-------AYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEK-GRRKCDQYWPA----
DGSEEYGNFLVTQ-KSVQV-LAYYTVRNFTLRNTKIKKGSQ---KGRPSGRVVTQYHYTQ
WPDMGVPEY--SLPVLTFVRKAAYAK-------------RHAVGPVVVHCSAGVGRTGTY
IVLDSMLQQIQH---EGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAIL
>rPTPzeta_D1_(NP_037212)_Ptprz1 .
KHFPKHVADLHASNG-FTEEFETLKEFYQEVQSC----TVDLGITADSSNHPDNKHK-NR
YVNIVAYDHSRVKLTQLAEKDG-------------------KLTDYINANYVDGYNRPK-
-------AYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEK-GRRKCDQYWPT----
DGSEEYGSFLVNQ-KNVQV-LAYYTVRNFTLRNTKIKKGSQ---KGRSSGRLVTQYHYTQ
WPDMGVPEY--SLPVLAFVRKTAQAK-------------RHAVGPVVVHCSAGVGRTGTY
IVLDSMLQQIQH---EGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAIL
>cPTPzeta_D1_(AAA49015) .
KHFPKHVADLHASNG--------FSEEFEEIQSC----TVDLGITSDSSNHPDNKNK-NR
YINIVAYDHTRVKLAQLAEKDG-------------------KLTDYINANYVDGYNKPK-
-------AYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLLEK-GRRKCDQYWPA----
EGSEEYGNFLVTQ-KSVHV-LAYYTVRNFTLRNTKIKKGSQ---KGRSSGRVVTQYHYTQ
WPDMGVPEY--TLPVLTFVRKASHAK-------------RHAVGPIVVHCSAGVGRTGTY
VVLDSMLQQIQH---EGTVNIFGFLKHIRTQRNYLVQTEEQYIFIHDALVEAIL
>xPTPzeta_D1_(BAA97445) .
KQFHKHVEDLHSRNG--------FTDEFEEVQNC----TTDLGITYENSNHPDNKNK-NR
YINIVAYDHSRVKLSQLAEKDG-------------------KATDYINANFVDGYNKQK-
-------AYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNLVEK-GRRKCDQYWPS----
DGSEEYGAFLVTQ-KTIKV-LAYYTVRTFTVRNNKIKKGSQ---KGRQNERAVVQYHYTQ
WPDMGVPEY--TLPVLTFVRKASAT---------------KLNGPVVVHCSAGVGRTGTY
IVLDSMLQQIQH---EGTVNIFGFLKHIRSQRNYLVQTEEQYIFIHDALVEAIL
>hCD45_D1_(NP_002829)_PTPRC .
DILLETYKRKIADEG------RLFLAEFQSIP------RVFSKFPIKEARKPFNQNK-NR
YVDILPYDYNRVELSEINGD---------------------AGSNYINASYIDGFKEPR-
-------KYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEG-NRNKCAEYWPSME--
EGTRAFGDVVVKINQHKR--CPDYIIQKLNIVNKKEKA----------TGREVTHIQFTS
WPDHGVPED--PHLLLKLRRRVNAFS-------------NFFSGPIVVHCSAGVGRTGTY
IGIDAMLEGLEA---ENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQ
>mCD45_D1_(NP_035340)_Ptprc .
DILLETYKRKIADEG------RLFLAEFQSIP------RVFSKFPIKDARKPHNQNK-NR
YVDILPYDYNRVELSEINGD---------------------AGSTYINASYIDGFKEPR-
-------KYIAAQGPRDETVDDFWRMIWEQKATVIVMVTRCEEG-NRNKCAEYWPSME--
EGTRAFKDIVVTINDHKR--CPDYIIQKLNVAHKKEKA----------TGREVTHIQFTS
WPDHGVPED--PHLLLKLRRRVNAFS-------------NFFSGPIVVHCSAGVGRTGTY
IGIDAMLEGLEA---EGKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQ
>rCD45_D1_(XP_213985)_Ptprc .
DLLLETYKRKIADEG------RLFLAEFQSIP------RVFSKFPIKDARKSQNQNK-NR
YVDILPYDYNRVELSEINGD---------------------AGSTYINASYIDGFKEPR-
-------KYIAAQGPRDETVDDFWKMIWEQKATVIVMVTRCEEG-NRNKCAEYWPCME--
EGTRTFRDVVVTINDHKR--CPDYIIQKLSIAHKKEKA----------TGREVTHIQFTS
WPDHGVPED--PHLLLKLRRRVNAFS-------------NFFSGPIVVHCSAGVGRTGTY
IGIDAMLESLEA---EGKVDVYGYVVNLRRQRCLMVQVEAQYILIHQALVEYNQ
>cCD45_D1_(A54080) .
EKLLETYKRKIADEG------RLFLDEFQSIP------RIFTKFPMKEAKRSHNQNK-NR
YIDILPYDHNRVELSEIPGD---------------------PGSDYINASYIDGFKEPR-
-------KYIAAQGPKDETTDDFWRMIWEQKATIIVMVTRCEEG-NRNKCAQYGPSME--
NGSATYGDITVKINESKI--CPDYIIQKLHITNGRERT----------SGRDVTHIQFTS
WPDHGVPED--PHLLLKLRRRVNALS-------------NFFSGPIVVHCSAGVGRTGTY
IGIDAMLEGLDA---EGRVDVYGYVVKLRRQRCLMVQVESQYILIHQALVEYHQ
>cypcaCD45_D1_(BAA92179) .
GGLVEAYKNKIADEG------RLFMDEFQSIP------RIFSNYTIKEAKKSENQYK-NR
YVDILPYDYNRVTLSTGGED------------------------NYINASFIEGYREPK-
-------KYIAAQGPKDETVVDFWRMVWEQKSSIIVMVTRCEEG-NKTKCAQYWPSLD--
REAEIFEEFVVKIRSEEH--CPDYVIRHLILNNKREKG----------SEREVTHIQFIS
WPDHGVPGD--PSLLLKLRRRVNSFK-------------NFFSGPVVVHCSAGVGRTGTY
MSIDAMIESLEA---EGRVDIYGFVAKLRRQRCLMVQVEAQYILIHTALIEYNQ
>fuCD45_D1_(CAB96211) .
ETLLDAYKRKIADEG------RLFLAEFQSIP------RIFSKYTVKEAKKSHNVPK-NR
YVDILPYDYNRVQLTTGNGS---------------------AGCDYINASFIDGFKELK-
-------KYIAAQGPKEETVSNFWRMIWEQQTSIIVMVSRCEEG-NRIKCAQYWPSED--
RDTEIFEEFIVKLTSEDH--YPDYIIRHLSLTNKKDKG----------SEREVTHIQFMS
WPDHGVPEE--AQLLLKLRRRVNSFK-------------NFFSGPIVVHCSAGVGRTGTY
IGIDAMMESLEA---EGRVDIYGYVVMLRRQRCLMVQVEAQYILIHQALLEHTQ
>sharkCD45_D1_(T43148) .
EQLIDVYRRKQADES------RLFLAEFQSIP------RVFSKFSVKEARRGCNTNK-NR
YVDILPYDHNRVQLSPIAGE---------------------QGSDYINASFIDGFNESR-
-------KYIAAQGPKEETSDDFWKMVWEQKATIIVMVTRCEEG-KRPKCAQYWPTMD--
SPSKTFGDLTVRISEEQW--CPDYVIRKLFISHKSEKT----------PEREVTHIQFIR
WPDHGVPED--PHLLLKLRQRVNAFR-------------NLFSGPIVVHCSAGVGRTGSY
IGIDAMMQGLEA---EGRVDVYGYIVQLRRQRCLMVQVEAQYILIHQALLEYYL
>hDEP1_D1_(NP_002834)_PTPRJ .
ENFEAYFKKQQADSN------CGFAEEYEDLK------LVGISQPKYAAELAENRGK-NR
YNNVLPYDISRVKLSVQTHS----------------------TDDYINANYMPGYHSKK-
-------DFIATQGPLPNTLKDFWRMVWEKNVYAIIMLTKCVEQ-GRTKCEEYWPS----
KQAQDYGDITVAMTSEIVL--PEWTIRDFTVKNIQT-----------SESHPLRQFHFTS
WPDHGVPDT--TDLLINFRYLVRDYMKQ-----------SPPESPILVHCSAGVGRTGTF
IAIDRLIYQIEN---ENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIVR
>rDEP1_D1_(NP_058965)_Ptprj .
ENFEAYFKKQQADSN------CGFAEEYEDLK------LIGISLPKYAAEIAENRGK-NR
YNNVLPYDISRVKLSVQTHS----------------------TDDYINANYMPGYHSKK-
-------DFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQ-GRTKCEEYWPS----
KQAQDYGDITVAMTSEVVL--PEWTIRDFVVKNMQS-----------SESHPLRQFHFTS
WPDHGVPDT--TDLLINFRYLVRDYMKQ-----------IPPESPILVHCSAGVGRTGTF
IAIDRLIYQIEN---ENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIR
>mDEP1_D1_(NP_033008)_Ptprj .
ENFEAYFKKQQADSN------CGFAEEYEDLK------LIGISLPKYTAEIAENRGK-NR
YNNVLPYDISRVKLSVQTHS----------------------TDDYINANYMPGYHSKK-
-------DFIATQGPLPNTLKDFWRMVWEKNVYAIVMLTKCVEQ-GRTKCEEYWPS----
KQAQDYGDITVAMTSEVVL--PEWTIRDFVVKNMQN-----------SESHPLRQFHFTS
WPDHGVPDT--TDLLINFRYLVRDYMKQ-----------IPPESPILVHCSAGVGRTGTF
IAIDRLIYQIEN---ENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDIIR
>hGLEPP1_D1_(NP_109592)_PTPRO .
DDFDAYIKDMAKDSD------YKFSLQFEELK------LIGLDIPHFAADLPLNRCK-NR
YTNILPYDFSRVRLVSMNEE---------------------EGADYINANYIPGYNSPQ-
-------EYIATQGPLPETRNDFWKMVLQQKSQIIVMLTQCNEK-RRVKCDHYWPFT---
EEPIAYGDITVEMISEEEQ--DDWACRHFRINYA-------------DEMQDVMHFNYTA
WPDHGVPTANAAESILQFVHMVRQQAT-------------KSKGPMIIHCSAGVGRTGTF
IALDRLLQHIRD---HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWM
>rGLEPP1_D1_(NP_059032)_Ptpro .
DDFDSYIKDMAKDSD------YKFSLQFEELK------LIGLDIPHFAADLPLNRCK-NR
YTNILPYDFSRVRLVSMNEE---------------------EGADYINANYIPGYNSPQ-
-------EYIATQGPLPETRNDFWKMVLQQKSRIIVMLTQCNEK-RRVKCDHYWPFT---
EEPIAYGDITVEMVSEEEQ--EDWASRHFRINYA-------------DEAQDVMHFNYTA
WPDHGVPPANAAESILQFVYTVRQQAT-------------KSKGPMIIHCSAGVGRTGTF
IALDRLLQHIRD---HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWL
>mPTPphi_D1_(NP_035346)_Ptpro .
DDFDSYIKDMAKDSD------YKFSLQFEELK------LIGLDIPHFAADLPLNRCK-NR
YTNILPYDFSRVRLVSMNEE---------------------EGADYINANYIPGYNSPQ-
-------EYIATQGPLPETRNDFWKMVLQQKSHIIVMLTQCNEK-RRVKCDHYWPFT---
EEPIAYGDITVEMVSEEEE--EDWASRHFRINYA-------------DEAQDVMHFNYTG
WPDHGVPPANAAESILQFVFTVRQQAA-------------KSKGPMIIHCSAGVGRTGTF
IALDRLLQHIRD---HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWL
>rabPTPoc_D1_(AAB16824) .
DDFDAYIKDMAKDSD------YKFSLQFEELK------LIGLDIPHFAADLPLNRCK-NR
YTNILPYDFSRVRLLSMNEE---------------------EGADYINANYIPGYNSPQ-
-------EYIATQGPLPETRNDFWKMVLQQKSQMIVMLTQCNEK-RRVKCDHYWPFT---
EEPIAYGDITVEMISEEEQ--DDWAHRHFRINYA-------------DEMQDVMHFNYTA
WPDHGVPTANAAESILQFVHMVRQQAT-------------KSKGPMIIHCSAGVGRTGTF
IALDRLLQHIRD---HEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWM
>hPTPbeta_D1_(NP_002828)_PTPRB .
NQFEGHFMKLQADSN------YLLSKEYEELK------DVGRNQSCDIALLPENRGK-NR
YNNILPYDATRVKLSNVDDD---------------------PCSDYINASYIPGNNFRR-
-------EYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEK-GRVKCDHYWPAD---
QDSLYYGDLILQMLSESVL--PEWTIREFKICGEEQL----------DAHRLIRHFHYTV
WPDHGVPET--TQSLIQFVRTVRDYINR-----------SPGAGPTVVHCSAGVGRTGTF
IALDRILQQLDS---KDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLR
>mPTPbeta_D1_(NP_084204)_Ptprb .
NQFEGHFMKLQADSN------YLLSKEYEDLK------DVGRSQSCDIALLPENRGK-NR
YNNILPYDASRVKLSNVDDD---------------------PCSDYINASYIPGNNFRR-
-------EYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEK-GRVKCDHYWPAD---
QDPLYYGDLILQMVSESVL--PEWTIREFKICSEEQL----------DAHRLIRHFHYTV
WPDHGVPET--TQSLIQFVRTVRDYINR-----------SPGAGPTVVHCSAGVGRTGTF
VALDRILQQLDS---KDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLR
>rPTPbeta_D1_(XP_235156_(revised)) .
NQFEGHFMKLQADSN------YLLSKEYEDLK------DVGRSQSCDIALLPENRGK-NR
YNNILPYDASRVKLCNVDDD---------------------PCSDYINASYIPGNNFRR-
-------EYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEK-GRVKCDHYWPAD---
QDPLYYGDLILQMVSESVL--PEWTIREFKICSEEQL----------DAHRLLRHFHYTV
WPDHGVPET--TQSLIQFVRTVRDYINR-----------SPGAGPTVVHCSAGVGRTGTF
VALDRILQQLDS---KDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLR
>hPTPS31_D1_(AR073855)_PTPGMC1 .
KSFLQHVEELCTNNN------LKFQEEFSELP------KFLQDLSSTDADLPWNRAK-NR
FPNIKPYNNNRVKLIADASV---------------------PGSDYINASYISGYLCPN-
-------EFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEK-GRIRCHQYWPEDN--
KPVTVFGDIVITKLMEDVQ--IDWTIRDLKIERH-------------GDCMTVRQCNFTA
WPEHGVPEN--SAPLIHFVKLVRASR-------------AHDTTPMIVHCSAGVGRTGVF
IALDHLTQHIND---HDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLS
>rPTPGMC1_D1_(NP_075214)_Ptprq .
KSFLQHVEELCTNSN------LKFQEEFSELP------KFLQDLSSTDADLPWNRAK-NR
FPNIKPYNNNRVKLIADVSL---------------------PGSDYINASYVSGYLCPN-
-------EFIATQGPLPGTVGDFWRMVWETRTKTLVMLTQCFEK-GRIRCHQYWPEDN--
KPVTVFGDIVITKLMEDIQ--IDWTIRDLKIERH-------------GDCMTVRQCNFTG
WPEHGVPEN--TTPLIHFVKLVRTSR-------------AHDTTPMVVHCSAGVGRTGVF
IALDHLTQHINN---HDFVDIYGLVAELRSERMCMVQNLAQYIFLHQCILDLLS
>hSAP1_D1_(NP_002833)_PTPRH .
EDFADHVRKNERDSN------CGFADEYQQLS------LVGHSQSQMVASASENNAK-NR
YRNVLPYDWSRVPLKPIHEE---------------------PGSDYINASFMPGLWSPQ-
-------EFIATQGPLPQTVGDFWRLVWEQQSHTLVMLTNCMEA-GRVKCEHYWPLDS--
-QPCTHGHLRVTLVGEEV--MENWTVRELLLLQVE-----------EQKTLSVRQFHYQA
WPDHGVPSS--PDTLLAFWRMLRQWLDQ-----------TMEGGPPIVHCSAGVGRTGTL
IALDVLLRQLQS---EGLLGPFSFVRKMRESRPLMVQTEAQYVFLHQCICGSSN
>mSAP1_D1_(BAC37443) .
KDFADHVRENEKDSN------CGFAEEYQQLA------LEGQGQSQITASALENRSK-NR
YRNVLPYDWSRVPLQPLQEE---------------------PGSDYINASFMPGLWSPK-
-------EFIATQGPLPNTVGDFWRMVWEQQSHTLVMLTNCMES-GRVKCEHYWPLDA--
-QPCIHGQLQVMLISEEA--SENWTVRHLQLFHMK-----------EQQTLSLRQFHYLA
WPDHGVPYS--PDPLLAFRKMLRQWMDQ-----------TTDGGPPIVHCSAGVGRTGTL
IALDVLLRQLEC---EGLVGPFSFVKKMRESRPLMVQTEAQYVFLHQCILKSLQ
>rPTPBEM2_D1_(NP_598276) .
KDFADHVRENEKDSN------CGFAEEYQQLA------LEGQGQSQMTALALENVSK-NR
YRNVLPYDWSRVPLQPLHEE---------------------PGSDYINASFMPGLWSPK-
-------EFIATQGPLPHTVSDFWRMVWEQQSHTLVMLANCMES-GQVKCEHYWPLDA--
-QPCTHGQLQVTLVSEEV--TENWTVRHLQLFHMK-----------EQQTLSVRQFHYVA
WPDHGVPYS--PDPLLAFQKLLRQWLDQ-----------TMDGGPPIVHCSAGVGRTGTL
IALDVLLRQLEC---EGLVDPFSFVKKMRESRPLMVQTEAQYVFLHQCILRSLQ
>mPTPESP_D1_(NP_031981)_Esp .
HSFRQSYEAKSARAH------QAFFQEFEELK------EVGKDQPRLEAEHPANITK-NR
YPHVLPYDHSRVRLTQLSGE---------------------PHSDYINANFIPGYSHPQ-
-------EIIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMEN-GRVLCEHYWPVNS--
-TPVTHGHITTHLLAEES--EDEWTRREFQLQHGA-----------EQKQRRVKQLQFTT
WPDHSVPEA--PSSLLAFVELVQEEVKA-----------TQGKGPILVHCSAGVGRTGTF
VALLPAVRQLEE---EQVVDVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKIL
>rOSTPTP_D1_(NP_149090)_Esp .
HSFRQSYEAKSAHAH------QTFFQEFEELK------EVGKDQPRLEAEHPDNIIK-NR
YPHVLPYDHSRVRLTQLPGE---------------------PHSDYINANFIPGYSHTQ-
-------EIIATQGPLKKTLEDFWRLVWEQQVHVIIMLTVGMEN-GRVLCEHYWPANS--
-TPVTHGHITIHLLAEEP--EDEWTRREFQLQHGT-----------EQKQRRVKQLQFTT
WPDHSVPEA--PSSLLAFVELVQEQVQA-----------TQGKGPILVHCSAGVGRTGTF
VALLRLLRQLEE---EKVADVFNTVYILRLHRPLMIQTLSQYIFLHSCLLNKIL
>hPCPTP1_D1_(NP_002840)_PTPRR .
SRILTRSQLRDVVASS-----HLLQSEFMEIP--------MNFVDPKEIDIPRHGTK-NR
YKTILPNPLSRVCLRPKNVTD--------------------SLSTYINANYIRGYSGKE-
------KAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKE--KNEKCVLYWPE----
-KRGIYGKVEVLVISVNE--CDNYTIRNLVLKQ-------------GSHTQHVKHYWYTS
WPDHKTPDS--AQPLLQLMLDVEEDRLA-----------SQGRGPVVVHCSAGIGRTGCF
IATSIGCQQLKE---EGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYES
>rPCPTP1_D1_(NP_446046)_Ptprr .
SRVLTSPQLRDVVASS-----HLLQSEFMEIP--------MNFVDPKEIDIPRHGTK-NR
YKTILPNPLSRVCLRPKNITD--------------------PLSTYINANYIRGYSGKE-
------KAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKE--KNEKCVLYWPE----
-KRGIYGKVEVLVIGVNE--CDNYTIRNLVLKR-------------GSHTQHVKHYWYTS
WPDHKTPDS--AQPLLQLMLDVEEDRLA-----------SEGRGPVVVHCSAGIGRTGCF
IATSIGCQQLKE---EGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFES
>mPTPSL_D1_(NP_035347)_Ptprr .
SRVLTRSQLRDVVASS-----HLLQSEFMEIP--------MNFVDPKEIDIPRHGTK-NR
YKTILPNPLSRVCLRPKNITD--------------------SLSTYINANYIRGYSGKE-
------KAFIATQGPMINTVNDFWQMVWQEDSPVIVMITKLKE--KNEKCVLYWPE----
-KRGIYGKVEVLVTGVTE--CDNYTIRNLVLKQ-------------GSHTQHVKHYWYTS
WPDHKTPDS--AQPLLQLMLDVEEDRLA-----------SEGRGPVVVHCSAGIGRTGCF
IATSIGCQQLKE---EGVVDALSIVCQLRVDRGGMVQTSEQYEFVHHALCLFES
>hSTEP_D1_(NP_116170)_PTPN5 .
SRVLQAEELHEKALDP-----FLLQAEFFEIP--------MNFVDPKEYDIPGLVRK-NR
YKTILPNPHSRVCLTSPDPDD--------------------PLSSYINANYIRGYGGEE-
------KVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEE--MNEKCTEYWPE----
-EQVAYDGVEITVQKVIH--TEDYRLRLISLKS-------------GTEERGLKHYWFTS
WPDQKTPDR--APPLLHLVREVEEAAQQE----------GPHCAPIIVHCSAGIGRTGCF
IATSICCQQLRQ---EGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEK
>mSTEP_D1_(NP_038671)_Ptpn5 .
SRVLRAEELHEKALDP-----FLLQAEFFEIP--------MNFVDPKEYDIPGLVRK-NR
YKTILPNPHSRVRLTSPDPED--------------------PLSSYINANYIRGYSGEE-
------KVYIATQGPIVSTVADFWRMVWQERTPIIVMITNIEE--MNEKCTEYWPE----
-EQVVHDGVEITVQKVIH--TEDYRLRLISLRR-------------GTEERTLKHYWFTS
WPDQKTPDR--APPLLHLVREVEEAAQQE----------GPHCSPIIVHCSAGIGRTGCF
IATSICCQQLRR---EGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEK
>rSTEP_D1_(NP_062126)_Ptpn5 .
SRVLRAEELHEKALDP-----FLLQAEFFEIP--------MNFVDPKEYDIPGLVRK-NR
YKTILPNPHSRVRLTSPDPED--------------------PLSSYINANYIRGYNGEE-
------KVYIATQGPIVSTVVDFWRMVWQERTPIIVMITNIEE--MNEKCTEYWPE----
-EQVVHDGVEITVQKVIH--TEDYRLRLISLRR-------------GTEERGLKHYWFTS
WPDQKTPDR--APPLLHLVREVEEAAQQE----------GPHCSPIIVHCSAGIGRTGCF
IATSICCQQLRR---EGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEK
>hHePTP_D1_(NP_002823)_PTPN7 .
HPLTRWALQRQPPSP------KQLEEEFLKIP--------SNFVSPEDLDIPGHASK-DR
YKTILPNPQSRVCLGRAQSQ---------------------EDGDYINANYIRGYDGKE-
------KVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLRE--GKEKCVHYWPT----
-EEETYGPFQIRIQDMKE--CPEYTVRQLTIQY-------------QEERRSVKHILFSA
WPDHQTPES--AGPLLRLVAEVEESPET-----------AAHPGPIVVHCSAGIGRTGCF
IATRIGCQQLKA---RGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAG
>mHePTP_D1_(NP_796055)_Ptpn7 .
HPLTRWTLQHQPPSP------KQLEEEFLKIP--------SNFVNPEDLDIPGHASK-DR
YKTILPNPQSRVCLGRAQSQ---------------------EDSDYINANYIRGYDGKE-
------KVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLRE--GKEKCVHYWPT----
-EEEAYGPFQIRIQDMKE--HPEYTVRQLTIQH-------------QQECRSVKHILFSA
WPDHQTPES--AGPLLRLVAEVETP-ET-----------AANSGPIVVHCSAGIGRTGCF
IATRIGCQQLKA---RGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAA
>rLCPTP_D1_(P49445)_Ptpn7 .
HPLTRWTLQHQPPSP------KQLEEEFLKIP--------SNFVNPEDLDIPGHASK-DR
YKTILPNPQSRVCLGRAHSQ---------------------EDSDYINANYIRGYDGKE-
------KVYIATQGPMPNTVADFWEMVWQEDVSLIVMLTQLRE--GKEKCVHYWPT----
-EEEAYGPFQIRIQGMKE--HPEYTVRHLTIQH-------------QQECRSVKHILFSA
WPDHQTPES--AGPLLRLVAEVETP-ET-----------AANSGPIVVHCSAGIGRTGCF
IATRIGCQQLKA---RGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAA
>hLyPTP_D1_(NP_057051)_PTPN22 .
EILQKFLDEAQSKKI----TKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKK-NR
YKDILPYDYSRVELSLITSD---------------------EDSSYINANFIKGVYGPK-
-------AYIATQGPLSTTLLDFWRMIWEYSVLIIGMACMEYEM-GKKKCERYWAEPV--
EMQLEFGPFSVSCEAEKRK--SDYIIRTLKVKFN-------------SETRTIYQFHYKN
WPDHDVPSS-----IDPILELIWDVRCYQ----------EDDSVPICIHCSAGCGRTGVI
CAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFK
>mPEP_D1_(NP_033005)_Ptpn8 .
EILQQLLKEAQKKKL----NSEEFASEFLKLKRQSTKYKADKIYPTTVAQRPKNIKK-NR
YKDILPYDHSLVELSLLTSD---------------------EDSSYINASFIKGVYGPK-
-------AYIATQGPLSTTLLDFWRMIWEYRILVIVMACMEFEM-GKKKCERYWAEPG--
ETQLQFGPFSISCEAEKKK--SDYKIRTLKAKFN-------------NETRIIYQFHYKN
WPDHDVPSS-----IDPILQLIWDMRCYQ----------EDDCVPICIHCSAGCGRTGVI
CAVDYTWMLLKDGIIPKNFSVFNLIQEMRTQRPSLVQTQEQYELVYSAVLELFK
>hPEST_D1_(NP_002826)_PTPN12 .
EILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKK-NR
YKDILPFDHSRVKLTLKTPS---------------------QDSDYINANFIKGVYGPK-
-------AYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEM-GRKKCERYWPLYG--
EDPITFAPFKISCEDEQAR--TDYFIRTLLLEFQ-------------NESRRLYQFHYVN
WPDHDVPSS-----FDSILDMISLMRKYQ----------EHEDVPICIHCSAGCGRTGAI
CAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE
>rRKPTP_D1_(NP_476456)_Ptpn12 .
EILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKK-NR
YKDILPFDHSRVKLTLKTPS---------------------QDSDYINANFIKGVYGPR-
-------AYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEM-GRKKCERYWPLYG--
EDPITFAPFKISCENEQAR--TDYFIRTLLLEFQ-------------NESRRLYQFHYVN
WPDHDVPSS-----FDSILDMISLMRKYQ----------EHEDVPICIHCSAGCGRTGAI
CAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE
>mPEST_D1_(NP_035333)_Ptpn12 .
EILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKK-NR
YKDILPFDHSRVKLTLKTPS---------------------QDSDYINANFIKGVYGPK-
-------AYVATQGPFRNTVIDFWRMIWEYNVVMIVMACREFEM-GRKKCERYWPLYG--
EDPITFAPFKISCENEQAR--TDYFIRTLLLEFQ-------------NESRRLYQFHYVN
WPDHDVPSS-----FDSILDMISLMRKYQ----------EHEDVPICIHCSAGCGRTGAI
CAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFE
>hBDP1_D1_(NP_055184)_PTPN18 .
DSARSFLERLEARGG---REGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRK-NR
YKDVLPYDQTRVILSLLQEE---------------------GHSDYINGNFIRGVDGSL-
-------AYIATQGPLPHTLLDFWRLVWEFGVKVILMACREIEN-GRKRCERYWAQE---
QEPLQTGLFCITLIKEKWL-NEDIMLRTLKVTFQ-------------KESRSVYQLQYMS
WPDRGVPSS--PDHMLAMVEEARRLQG-------------SGPEPLCVHCSAGCGRTGVL
CTVDYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFC
>mPTPK1_D1_(NP_035336)_Ptpn18 .
DLVRSLLEQLEARDY---REGAILAREFSDIKARSVAWKSEGVCSTKAGSRLGNTNK-NR
YKDVVAYDETRVILSLLQEE---------------------GHGDYINANFIRGIDGSQ-
-------AYIATQGPLPHTLLDFWRLVWEFGVKVILMACQETEN-GRRKCERYWARE---
QEPLKAGPFCITLTKETTL-NADITLRTLQVTFQ-------------KEFRSVHQLQYMS
WPDHGVPSS--SDHILTMVEEARCLQG-------------LGPGPLCVHCSAGCGRTGVL
CAVDYVRQLLLTQTIPPNFSLFQVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFS
>rPTP20_D1_(AAC52896) .
DLVRSFLEQQEARDH---RKGAILAREFSDIKARSVAWKTEGVCSTKAGSQQGNSKK-NR
YKDVVPYDETRVILSLLQEE---------------------GHGDYINANFIRGTDGSQ-
-------AYIATQGPLPHTLLDFWRLVWEFGIKVILMACQETEN-GRRKCERYWAQE---
REPLQAGPFCITLTKETAL-TSDITLRTLQVTFQ-------------KESRPVHQLQYMS
WPDHGVPSS--SDHILTMVEEARCLQG-------------LGPGPLCVHCSAGCGRTGVL
CAVDYVRQLLLTQTIPPNFSLFEVVLEMRKQRPAAVQTEEQYRFLYHTVAQLFS
>hSHP1_D1_(NP_002822)_PTPN6 .
ADIENRVLELNKKQESEDTAKAGFWEEFESLQKQ----EVKNLHQRLEGQRPENKGK-NR
YKNILPFDHSRVILQGRDSNI--------------------PGSDYINANYIKNQLLGPD
EN---AKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEK-GRNKCVPYWPE---V
GMQRAYGPYSVTNCGEHD--TTEYKLRTLQVSPLDNGDLIR----------EIWHYQYLS
WPDHGVPSE--PGGVLSFLDQINQRQES-----------LPHAGPIIVHCSAGIGRTGTI
IVIDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIE
>mSHP1_D1_(NP_038573)_Hcph .
ADIENRVLELNKKQESEDTRKAGFWEEFESLQKQ----EVKNLHQRLEGQRPENKSK-NR
YKNILPFDHSRVILQGRDSNI--------------------PGSDYINANYVKNQLLGPD
EN---SKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEK-GRNKCVPYWPE---V
GTQRVYGLYSVTNSREHD--TAEYKLRTLQISPLD----NGDLVR------EIWHYQYLS
WPDHGVPSE--PGGVLSFLDQINQRQES-----------LPHAGPIIVHCSAGIGRTGTI
IVIDMLMESISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIE
>rSHP1_D1_(NP_446360)_Ptph6 .
ADIENRVLELNKKQESEDTAKAGFWEEFESLQKQ----EAKNLHQRLEGQRPENKSK-NR
YKNILPFDHSRVILQGRDSNI--------------------PGSDYINANYVKNQLLGPD
EN---SKTYIASQGCLDATVNDFWQMAWQENTRVIVMTTREVEK-GRNKCVPYWPE---V
GTQRVYGLYSVTNCKEHD--TAEYKLRTLQISPLD----NGDLVR------EIWHYQYLS
WPDHGVPSE--PGGVLSFLDQINQRQES-----------LPHAGPIIVHCSAGIGRTGTI
IVIDMLMESVSTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIE
>zSHP1_D1_(AAH44414) .
VNQLDQTSEREKMDGADKKIKAGFWEEFDALQKL----ETKVTKSRDEGMRPENKSK-NR
YKNILPFDETRVILENADPNV--------------------VGSDYINANYVINKLMVTN
PQ----KTYIACQGCLATTVDDFWQMMWQEDSRVIVMTTREVEK-GRNKCVPYWPT--TE
GESKEVGRYVVKLLSEMD--AADYKVRVVELTAPH----RNEAPR------KIWHFQYLS
WPDHGVPQE--PGGVLSFLDQVNRKQEE-----------LRSSAPIVIHCSAGIGRTGTI
VVIDMLIDSIDAKGLDCDIDIQKCIMMVRDQRSGMVQTEAQYKFIYLAVLQYVE
>ryPTPN6c_D1_(BAA95199) .
-----------------------------LLQQQ----EYKLLYSRKEGQRIENKSK-NR
YKNILPFDNTRVRLKEVDESV--------------------VGSDYINANNITNGKNGDD
-----CKNYIATQGCLQNTINDFWKMIYQENAHVIVMTTKEIER-GKCKCVRYWPD---V
KTSTEYGMISVRNLEERM--AQDYIVRDLEVMRLD----WNERPR------HVWHYQYLS
WPDHGVPNE--PGGVLSFLDQVNRTQQS-----------IPDTGPIIVHCSAGIGRTGTI
IVIDMLISDISRQGLDCDIDIPKTIQIVRKQRSGMVQTEAQYKFIYMAVQQYIE
>hSHP2_D1_(NP_002825)_PTPN11 .
AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ----ECKLLYSRKEGQRQENKNK-NR
YKNILPFDHTRVVLHDGDPNE--------------------PVSDYINANIIMPEFETKC
NNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
YALKEYGVMRVRNVKESA--AHDYTLRELKLSKVG----QGNTER------TVWQYHFRT
WPDHGVPSD--PGGVLDFLEEVHHKQES-----------IMDAGPVVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>mSHP2_D1_(NP_035332)_Ptpn11 .
AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ----ECKLLYSRKEGQRQENKNK-NR
YKNILPFDHTRVVLHDGDPNE--------------------PVSDYINANIIMPEFETKC
NNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
YALKEYGVMRVRNVKESA--AHDYTLRELKLSKVGQALLQGNTER------TVWQYHFRT
WPDHGVPSD--PGGVLDFLEEVHHKQES-----------IVDAGPVVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>rSHP2_D1_(NP_037220)_Ptpn11 .
AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ----ECKLLYSRKEGQRQENKNK-NR
YKNILPFDHTRVVLHDGDPNE--------------------PVSDYINANIIMPEFETKC
NNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
CALKEYGVMRVRNVRESA--AHDYTLRELKLSKVG----QGNTER------TVWQYHFRT
WPDHGVPSD--PGGVLDFLEEVHHKQES-----------IVDAGPVVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>cSHP2_D1_(JC5167) .
AEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ----ECKLLYSRKEGQRQENKNK-NR
YKNILPFDHTRVVLHDGDPNE--------------------PVSDYINANIIMPEFETKC
NNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
YSLKEYGVMRVRNVKESA--AHDYTLRELKLSKVG----QGNTER------TVWQYHFRT
WPDHGVPSD--PGGVLDFLEEVHHKQES-----------ISDAGPVVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>zSHP2_D1_(AAH45328) .
AEIESRVRELSKLAEATDKVKQGFWEEFETLQQQ----ECKLLYSRKEGQRPENKNK-NR
YKNILPFDHTRVVLTDGDVNE--------------------QGSDYINANLIMPDNEAKS
NNSKLKRSYIATQGCLQNTISDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---V
SALKEYGAMRVRNVKETM--AHDYILRELKLSKVG----QGNTER------TVWQYHFRA
WPDHGVPGD--PGGVLDFLEEVKLKQEG-----------ITGAGPIVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>xSHP2_D1_(A55651) .
AEIEIRVKELSKPAETADKFKQGFWEEFETLQQQ----ECKLLYSRKEGQRPENKNK-NR
YKNILPFDHTRVELHDGDPNE--------------------QVSDYINANIIMPEFEIKC
INPKPKKRYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
FALKEYGVMRVRNVKETP--AHDYILRELKLSKVG----QGNTER------AVWQYHFKT
WPDHGVPAD--PGGVLDFLEEVHHKQDG-----------ITDAGPVVVHCSAGIGRTGTF
IVIDILIDVIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>ryPTPN6b_D1_(BAA95198) .
-----------------------------TLQQQ----ECKLLYSRKDGQRQENKYK-NR
YKNILPFDHTRVVLHDGDVTE--------------------PGSDYINANFILHDIDSNR
TTTKPKKTYIATQGCLHDTVNDFWRMVFQENSRVIVMTTKEVER-GKSKCVKYWPD---E
MSSKEYGAMRVKNVRENP--AHDYILRELKLSKVG----QGSTER------TVWQYHFKT
WPDHGVPSD--PGGVLDFLEEVNIKQEN-----------IPEAGPIVVHCSAGIGRTGTF
IVIDILIDIIREKGVDCDIDVPKSIQMVRSQRSGMVQTEAQYRFIYMAVQHYIE
>hPTPD1_D1_(NP_008970)_PTPN21 .
ATNDERCKILEQRLE-----QGMVFTEYERILK-----KRLVDGECSTARLPENAER-NR
FQDVLPYDDARVELVPTKEN----------------------NTGYINASHIKVSVSGIE
------WDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEG-GREKSFRYWPRLGSR
HNTVTYGRFKITTRFRTD--SGCYATTGLKMKHLLTG-----------QERTVWHLQYTD
WPEHGCPED--LKGFLSYLEEIQSVRRHTNSTS---D-PQSPNPPLLVHCSAGVGRTGVV
ILSEIMIACLEHN---EVLDIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQFLK
>mPTPRL10_D1_(NP_036007)_Ptpn21 .
ATNDERCKVLEQRLE-----QGMVFTEYERILK-----KRLVDGECSTARLPENAER-NR
FQDVLPYDDARVELVPTKEN----------------------NTGYINASHIKVSVSGIE
------WDYIATQGPLQNTCQDFWQMVWEQGVAIIAMVTAEEEG-GREKSFRYWPRLGSR
HNTVTYGRFKITTRFRTD--SGCYATTGLKMKHLLTG-----------QERTVWHLQYTD
WPEHGCPED--LKGFLSYLEEIQSVRRHTNSTS---E-PKSHNPPLLVHCSAGVGRTGVV
ILSEIMVACLEHN---EVLDIPRVLDMLRQQRMMLVQTLGQYTFVYRVLIQFLK
>rPTP2E_D1_(NP_598229)_Ptp2E .
ATNDERCKVLEQRLE-----QGTVFTEYERILK-----KRLVDGECSTARLPENAER-NR
FQDVLPYDDARVELVPTKEN----------------------NTGYINASHIKVSVSGIE
------WDYIATQGPLQNTCQDFWQMVWEQGVAIIAMVTAEEEG-GREKSFRYWPRLGSR
HNTVTYGRFKITTRFRTD--SGCYATTGLKMKHLLTG-----------QERTVWHLQYTD
WPEHGCPED--LKGFLSYLEEIQSVRRHTNSTS---E-PRSPNPPLLVHCSAGVGRTGVV
ILSEIMVACLEHN---EVLDIPRVLELLRQQRMMLVQTLSQYTFVYRVLIQFLK
>hPTPD2_D1_(NP_005392)_PTPN14 .
VPMDERFRTLKKKLE-----EGMVFTEYEQIP------KKKANGIFSTAALPENAER-SR
IREVVPYEENRVELIPTKEN----------------------NTGYINASHIKVVVGGAE
------WHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEG-GRTKSHRYWPKLGSK
HSSATYGKFKVTTKFRTD--SVCYATTGLKVKHLLSG-----------QERTVWHLQYTD
WPDHGCPED--VQGFLSYLEEIQSVRRHTNSML---EGTKNRHPPIVVHCSAGVGRTGVL
ILSELMIYCLEHN---EKVEVPMMLRLLREQRMFMIQTIAQYKFVYQVLIQFLQ
>mPTP36_D1_(NP_033002)_Ptpn14 .
VPIDERLRALKKKLE-----DGMVFTEYEQIP------NKKANGVFSTATLPENAER-SR
IREVVPYEENRVELIPTKEN----------------------NTGYINASHIKVVVGGSE
------WHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEEG-GRTKSHRYWPKLGSK
HSSATYGKFKVTTKFRTD--SGCYATTGLKVKHLLSG-----------QERTVWHLQYTD
WPHHGCPED--VQGFLSYLEEIQSVRRHTNSVL---EGIRTRHPPIVVHCSAGVGRTGVV
ILSELMIYCLEHN---EKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQ
>rPTPD2_D1_(XP_223062_(revised)) .
VPMDERLRALKKKLE-----DGMVFTEYEQIP------NKKANGIFSTATLPENAER-SR
IREVVPYEENRVELIPTKEN----------------------NTGYINASHIKVVVGGSE
------WHYIATQGPLPHTCHDFWQMVWEQGVNVIAMVTAEEAG-GRTKSHRYWPKLGSK
HSSATYGKFKVTTKFRTD--SGCYATTGLKVKHLLSG-----------QERTVWHLQYTD
WPHHGCPED--VQGFLSYLEEIQSVRRHTNSVL---EGVKTRHPPIVVHCSAGVGRTGVV
ILSELMIYCLEHNEKATKVEVPTMLRFLREQRMFMIQTIAQYKFVYQVLVQFLQ
>hMEG1_D1_(NP_002821)_PTPN4 .
HSLRESMIQLAEGLI-----TGTVLTQFDQLY------RKKPGMTMSCAKLPQNISK-NR
YRDISPYDATRVILKG--------------------------NEDYINANYINMEIPSSS
----IINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVER-GRVKCHQYWPEP---
TGSSSYGCYQVTCHSEEG--NTAYIFRKMTLFNQEKN-----------ESRPLTQIQYIA
WPDHGVPDD--SSDFLDFVCHVRNKR-------------AGKEEPVVVHCSAGIGRTGVL
ITMETAMCLIECN---QPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYE
>mMEG1_D1_(NP_064317)_Ptpn4 .
HSLRESMIQLAEGLI-----TGTVLAQFDQLY------RKKPGMTMSCAKLPQNISK-NR
YRDISPYDATRVLLKG--------------------------NEDYINANYINMEIPSSS
----IINQYIACQGPLPHTCKDFWQMIWEQGSSMVVMLTTQVER-GRVKCHQYWPEP---
SESSSYGCYQATCHSEEG--NPAYIFRKMTLINQEKN-----------ESRQLTQIQYTA
WPDHGVPDD--SSDFLDFVCHVRDQR-------------AGKEEPIIVHCSAGIGRTGVL
ITMETAMCLIECN---QPVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKVYE
>zMEG1_D1_(CAD43435) .
DAWRDSMLYLKEGLN-----SGTILAQFDQLY------RKRPGMTMSCAKLPQNISK-NR
YRDISPYDATRVILKG--------------------------TEDYINANYINMEIPACS
----LINRYIACQGPLPNTCSDFWQMTWEQGSSMVVMLTTQV------KCHQYWPNP---
SGSATYGGFQISCQTEEG--NSAFLVREITLTHIESG-----------ESRELTQIQYLA
WPDHGVPDD--STDFLDFVALVRNKR-------------AGKDEPVVVHCSAGIGRTGVL
ITMETAMCLMECS---QPVFPLEIVRTMRDQRAMMIQTPSQFKFVCEAILKVYE
>hPTPH1_D1_(NP_002820)_PTPN3 .
DTLEGSMAQLKKGLE-----SGTVLIQFEQLY------RKKPGLAITFAKLPQNLDK-NR
YKDVLPYDTTRVLLQG--------------------------NEDYINASYVNMEIPAAN
----LVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTER-GRTKCHQYWPDP---
PDVMNHGGFHIQCQSEDC--TIAYVSREMLVTNTQTG-----------EEHTVTHLQYVA
WPDHGVPDD--SSDFLEFVNYVRSLR--------------VDSEPLLVHCSAGIGRTGVL
VTMETAMCLTERN---LPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYE
>mPTPH1_D1_(XP_143789)_Ptpn3 .
DSLEGSMELLKKGLE-----SGTVLIQFEQLY------RKKPGLAVSFAKLPQNLDK-NR
YKDVLPYDTTRVLLQG--------------------------NEDYINASYVNMEMPAAN
----LVNKYIATQGPLPNTCAQFWQVVWDQKLSLVVMLTTLTER-GRTKCHQYWPDP---
PDIMDHGIFHIQCQTEDC--TIAYVSREMLVTNTETG-----------EEHTVTHLQYVA
WPDHGVPDD--SSDFLEFVKYVRSLR--------------VDGEPALVHCSAGIGRTGVL
VTMETAMCLIERN---LPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYE
>hPTPBAS_D1_(NP_006255)_PTPN13 .
ANLKSVIRVLRGLLD-----QGIPSKELENLQ------ELKPLDQCLIGQTKENRRK-NR
YKNILPYDATRVPLGD--------------------------EGGYINASFIKIPVGKEE
------FVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEG-EKIKCQRYWP-NILG
KTTMVSNRLRLALVRMQQ--LKGFVVRAMTLEDIQTR-----------EVRHISHLNFTA
WPDHDTPSQ--PDDLLTFISYMRHI---------------HRSGPIITHCSAGIGRSGTL
ICIDVVLGLISQD---LDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT
>mPTPBL_D1_(NP_035334)_Ptpn13 .
TQLQATIRTLQGLLD-----QGIPSKELENLQ------ELKPLDQCLIGQTKENRRK-NR
YKNILPYDTTRVPLGD--------------------------EGGYINASFIRIPVGTQE
------FVYIACQGPLPTTVGDFWQMVWEQNSTVIAMMTQEVEG-EKIKCQRYWP-SILG
TTTMANERLRLALLRMQQ--LKGFIVRVMALEDIQTG-----------EVRHISHLNFTA
WPDHDTPSQ--PDDLLTFISYMRHI---------------RRSGPVITHCSAGIGRSGTL
ICIDVVLGLISQD---LEFDISDLVRCMRLQRHGMVQTEGQYVFCYQVILYVLT
>bPTPBA14_D1_(NP_777015)_PTPN13 .
AKLKSVIRMLRGLLD-----QGIPSKELENLQ------ELKPLDQCLIGQTKENRRK-NR
YKNILPYDATRVPLGD--------------------------EGGYINASFIKIPVGREE
------FVYIACQGPLPTTVGDFWQMIWEQNSSVIAMMTQEVEG-EKIKCQRYWP-NVLG
KSTMVSNRLRLALVRVQQ--LKGFVVRAMTLEDIQTG-----------EVRHVSHLNFTA
WPDHDTPSQ--PDDLLTFISYMRHV---------------HRSGPIITHCSAGIGRSGTL
ICIDVVLGLISQD---LEFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT
>hPTPTyp_D1_(AL050040)_PTPN20 .
TAIKDCLKILEEKTA-----AYDIMQEFMALE------LKNLPGEFYSGNQPSNREK-NR
YRDILPYDSTRVPLGK--------------------------SKDYINASYIRIVNCGEE
------YFYIATQGPLLSTIDDFWQMVLENNSNVIAMITREMEG-GIIKCYHYWP--ISL
KKPLELKHFRVFLENYQI--LQYFIIRMFQVVEKSTG-----------TSHSVKQLQFTK
WPDHGTPAS--ADSFIKYIRYARKS---------------HLTGPMVVHCSAGIGRTGVF
LCVDVVFCAIVKD---CSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLR
>mPTPTyp_D1_(NP_033004)_Ptpn20 .
SAMRDCLNTLQKKEE------LDIIREFLELE------QMTLPDDFNSGNTLQNRDK-NR
YRDILPYDSTRVPLGK--------------------------NKDYINASYIRIVNHEEE
------YFYIATQGPLPETIEDFWQMVLENNCNVIAMITREIEC-GVIKCYSYWP--ISL
KEPLEFEHFSVFLETFHV--TQYFTVRVFQIVKKSTG-----------KSQCVKHLQFTK
WPDHGTPAS--ADFFIKYVRYVRKS---------------HITGPLLVHCSAGVGRTGVF
ICVDVVFSAIEKN---YSFDIMNIVTQMRKQRCGMIQTKEQYQFCYEIVLEVLQ
>cPTP1B_D1_(O13016) .
MEIEKEFHRLDQAAS--------WAAIYQDIR------HEASDFPCKVAKHPRNKNR-NR
YRDVSPFDHSRIKLNQG-------------------------DNDYINASLIKMEEAQR-
-------SYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEK-GSIKCAQYWPRKEEK
EMFFEDTNLKLTLISEDI--KSYYTVRQLELENLTTQ-----------ETREILHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LNPEYGPVVVHCSAGIGRSGTF
CLVDTCLLLMDKRKDPSSVDVKQVLLEMRKYRMGLIQTADQLRFSYLAVIEGAK
>hPTP1B_D1_(NP_002818)_PTPN1 .
MEMEKEFEQIDKSGS--------WAAIYQDIR------HEASDFPCRVAKLPKNKNR-NR
YRDVSPFDHSRIKLHQEDN-------------------------DYINASLIKMEEAQR-
-------SYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEK-GSLKCAQYWPQKEEK
EMIFEDTNLKLTLISEDI--KSYYTVRQLELENLTTQ-----------ETREILHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LSPEHGPVVVHCSAGIGRSGTF
CLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAK
>mPTP1B_D1_(NP_035331)_Ptpn1 .
MEMEKEFEEIDKAGN--------WAAIYQDIR------HEASDFPCKVAKLPKNKNR-NR
YRDVSPFDHSRIKLHQEDN-------------------------DYINASLIKMEEAQR-
-------SYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEK-GSLKCAQYWPQQEEK
EMVFDDTGLKLTLISEDV--KSYYTVRQLELENLTTK-----------ETREILHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LSLEHGPIVVHCSAGIGRSGTF
CLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAK
>rPTP1B_D1_(NP_036769)_Ptpn1 .
MEMEKEFEQIDKAGN--------WAAIYQDIR------HEASDFPCRIAKLPKNKNR-NR
YRDVSPFDHSRIKLHQEDN-------------------------DYINASLIKMEEAQR-
-------SYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRIMEK-GSLKCAQYWPQKEEK
EMVFDDTNLKLTLISEDV--KSYYTVRQLELENLATQ-----------EAREILHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LSPEHGPIVVHCSAGIGRSGTF
CLADTCLLLMDKRKDPSSVDIKKVLLEMRRFRMGLIQTADQLRFSYLAVIEGAK
>zPTP1B_D1_(NP_570999)_ptp1b .
--MEAEFREIDEHGN--------WNDVYQEIR------QQSSDLPCKIAKLPENRSR-NR
YRDVSPFDHSRICLQIGCN-------------------------DYINASLISVEEAQR-
-------KYILTQGPLPNTCGHFWEMVWEQRSRGVVMLNRVIEK-GSVKCAQYWPQREER
EAVFEDTNFRLTLISEDV--KSYYTVRQLELENLSTQ-----------ETREILHFHYTT
WPDFGVPES--PASFLNFLFKVRESGC-----------LSPELGPVVVHCSAGIGRSGTF
CLVDTCLLLMSQRKDPSSVRIQEVLLEMRRYRMGLIQTADQLRFSYLAFIEGAK
>hTCPTP_D1_(NP_002819)_PTPN2 .
TTIEREFEELDTQRR--------WQPLYLEIR------NESHDYPHRVAKFPENRNR-NR
YRDVSPYDHSRVKLQNAEN-------------------------DYINASLVDIEEAQR-
-------SYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEK-ESVKCAQYWP-TDDQ
EMLFKETGFSVKLLSEDV--KSYYTVHLLQLENINSG-----------ETRTISHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LNPDHGPAVIHCSAGIGRSGTF
SLVDTCLVLMEKG---DDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAK
>mTCPTP_D1_(NP_033003)_Ptpn2 .
ATIEREFEELDAQCR--------WQPLYLEIR------NESHDYPHRVAKFPENRNR-NR
YRDVSPYDHSRVKLQSTEN-------------------------DYINASLVDIEEAQR-
-------SYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRTVEK-ESVKCAQYWP-TDDR
EMVFKETGFSVKLLSEDV--KSYYTVHLLQLENINTG-----------ETRTISHFHYTT
WPDFGVPES--PASFLNFLFKVRESGC-----------LTPDHGPAVIHCSAGIGRSGTF
SLVDTCLVLMEKG---EDVNVKQLLLNMRKYRMGLIQTPDQLRFSYMAIIEGAK
>rTCPTP_D1_(NP_446442)_Ptpn2 .
ATIEREFEELDAQCR--------WQPLYLEIR------NESHDYPHRVAKFPENRNR-NR
YRDVSPYDHSRVKLQSAEN-------------------------DYINASLVDIEEAQR-
-------SYILTQGPLPNTCCHFWLMVWQQKTRAVVMLNRTVEK-ESVKCAQYWP-TDDR
EMVFKETGFSVKLLSEDV--KSYYTVHLLQLENINSG-----------ETRTISHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LNPDHGPAVIHCSAGIGRSGTF
SLVDTCLVLMEKG---EDVNVKQILLSMRKYRMGLIQTPDQLRFSYMAIIEGAK
>zTCPTP_D1_(AAH44373) .
--MEQEFEDIDSEGR--------WQNIYLEIR------NQSHECAFKVAKYPENRIR-NR
YRDVSPFDHSRVKLENTEN-------------------------DYINASLVVMEEAQR-
-------RYILTQGPLRNTCGHFWLMIWEQKTKAVIMLNRVIEK-GSEKCAQYWPTQEER
EMSFRDTRFVVTLVSEDV--KSYYTTRVLELQNANTG-----------ETREIYHFHYTT
WPDFGVPES--PASFLNFLFKVRESGS-----------LGMEQGPAVVHCSAGIGRSGTF
SLVDTCLVLMDKRKDPLLVDIKKILLDMRKYRMGLIQTPDQLRFSYMAVLEGAK
>hMEG2_D1_(NP_002824)_PTPN9 .
MTIQELVDYVNARQK------QGIYEEYEDIR------RENPVGTFHCSMSPGNLEK-NR
YGDVPCLDQTRVKLTKRSGH---------------------TQTDYINASFMDGYKQKN-
-------AYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEG-GRRKCGQYWP--LEK
DSRIRFGFLTVTNLGVEN--MNHYKKTTLEIHNTEER-----------QKRQVTHFQFLS
WPDYGVPSS--AASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTF
CSLDICLAQLEEL---GTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAE
>mMEG2_D1_(NP_062625)_Ptpn9 .
MTIQELVDYVNTRQK------RGIYEEYEDIC------LENPVGTFHRTMSPRNLEK-NR
YGDVPCLDQTRVKLTKRSGH---------------------TQTDYINASFMDGYKQKN-
-------AYNGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEG-GRRKCGQYWP--LEK
DSRIRFGFLTVTNLGVEN--MNHYKKTTLEIHNTEER-----------QKRQVTHFQFLS
WPDYGVPSS--AASLIDFLRVVRNQQSMAVGNMGARSKGQCPEPPIVVHCSAGIGRTGTF
CSLDICLAQLEEL---GTLNVFHTVSRMRTQRAFSIQTPEQYYFCYKAILEFAQ
>xPTPX10_D1_(B53978) .
MMVLDLVQHVKRMKK------RGIFQEYEEIR------KDPPVGSFDISKKSHNQVK-NR
YSDVLCLDQSRVKLGLVGTD---------------------ETTDYINASFMDGYKRKN-
-------AYIATQGPLPKTFDDFWRMVWEQKVLIIVMTTRVIER-GRIKCGQYWP--LEA
GRSEDTGHFIIRNIHIDL--FQDFKLTHFEVYNKQTD-----------ESRSVAHYQYMS
WPDFGVPKS--ASAMLDFRSQVKQHQAVAVQNLGMEWTGHPAGPPIVVHCSAGIGRTGTF
CTLDICLSRLEDI---GTVDVLQTVKRMRTQASFSIQTWDQYYFCYMAIIEYAQ
>xPTPX1_D1_(AAH43621) .
MMVLGLVQHVKRMKK------RGIFQEYEEIR------KDPPVGSFDISKKSHNQAK-NR
YSDVLCLDQSRVKLGLVGTD---------------------ETTDYINASFMDGYKRKN-
-------AYIATQGPLPKTFDDFWRMVWEQKVLIIVMTTRVIER-GRIKCGQYWP--LEA
GRSEDTGHFIIRNIHIDL--FQDFKLTHLEVYNKQTD-----------ESQSVAHYQYMS
WPDFGVPKS--ASAMLDFRTQVKQHQAVAVQALGMAWTGHPAGPPVVVHCSAGIGRTGTF
CTLDICLSRLEDI---GTVDVLQTVKRMRTQRAFSIQTWDQYYFCYMAIIEYAQ
>hHDPTP_D1_(NP_056281)_PTPN23 .
ERLRQLQQELEAFRG-----QLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLK-NR
HQDVMPYDSNRVVLRSGK-------------------------DDYINASCVEGLSPYCP
-------PLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEM-EKQKVARYFP--TER
GQPMVHGALSLALSSVRS--TETHVERVLSLQFRDQS-----------LKRSLVHLHFPT
WPELGLPDS--PSNLLRFIQEVHAHYLHQR----------PLHTPIIVHCSSGVGRTGAF
ALLYAAVQEVEAG--NGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVE
>mHDPTP_D1_(AAH22721) .
ERLQQLQQELEAFRG-----QLGDAGALDAIWRELQEAQEHDARGRSIAIARCYSLK-NR
HQDVMPYDSNRVVLRSGK-------------------------DDYINASCVEGLSPYCP
-------PLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEM-EKQKVARYFP--TER
GQPMVHGALSVALSSIRT--TETHVERVLSLQFRDQS-----------LKRSLVHLHFPT
WPELGLPDS--PGNLLRFIQEVHAHYLHQR----------PLHTPIVVHCSSGVGRTGAF
ALLYAAVQEVEAG--NGIPELPQLVRRMRQQRKHMLQEKLHLKFCHEALVRHVE
>rPTPTD14_D1_(T14355) .
ERLQKLQQELESFRG-----QLGDAGALDAVWRELQEAQEHDARGRSIAIARCYSLK-NR
HQDVMPYDSNRVVLRSGK-------------------------DDYINASCVEGLSPYCP
-------PLVATQRPLPGTAADFWLMVHEQKVSVIVMLVSEAEM-EKQKVARYFP--IER
GQPMVHGALSVALSSVRT--TDTHVERVLSLQFRDQS-----------LKRSLVHLHFPT
WPELGLPDS--PGNLLRFIQEVHAHYLHQR----------PLHTPIVVHCSSGVGRTGAF
ALLYAAVQEVEAG--SRIPELPQLVRRMRQQRKHMLQEKLHLKVLPRGIGATCG
>hIA2_D1_(NP_002837)_PTPRN .
HMILAYMEDHLRNRD-------RLAKEWQALCAY-----QAEPNTCATAQGEGNIKK-NR
HPDFLPYDHARIKLKVESSP---------------------SRSDYINASPIIEHDPRMP
-------AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED-GVKQCDRYWP----D
EGASLYHVYEVNLVSEHIW-CEDFLVRSFYLKNVQT-----------QETRTLTQFHFLS
WPAEGTPAS--TRPLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRTGTY
ILIDMVLNRMAKG--VKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVN
>mIA2_D1_(NP_033011)_Ptprn .
HMILAYMEDHLRNRD-------RLAKEWQALCAY-----QAEPNTCAAAQDESNIKK-NR
HPDFLPYDHARIKLKVESSP---------------------SRSDYINASPIIEHDPRMP
-------AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED-GVKQCDRYWP----D
EGSSLYHVYEVNLVSEHIW-CEDFLVRSFYLKNVQT-----------QETRTLTQFHFLS
WPAEGTPAS--TRPLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRTGTY
ILIDMVLNRMAKG--VKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVN
>rIA2_D1_(NP_446333)_Ptprn .
HMILAYMEDHLRNRD-------RLAKKWQALCAY-----QAEPNTCATAQGEGNIKK-NR
HPDFLPYDHARIKLKVESSP---------------------SRSDYINASPIIEHDPRMP
-------AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED-GVKQCDRYWP----D
EGSSLYHVYEVNLVSEHIW-CEDFLVRSFYLKNVQT-----------QETRTLTQFHFLS
WPAEGTPAS--TRPLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRTGTY
ILIDMVLNRMAKG--VKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVN
>bIA2_D1_(P56722)_Ptprn .
HMILAYMEDHLRNRD-------RLAKEWQALCAY-----QAEPNTCATAQGEGNIKK-NR
HPDFLPYDHARIKLKVESSP---------------------SRSDYINASPIIEHDPRMP
-------AYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVED-GVKQCDRYWP----D
EGSSLYHVYEVNLVSEHIW-CEDFLVRSFYLKNVQT-----------QETRTLTQFHFLS
WPAEGTPAS--TRPLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRTGTY
ILIDMVLNRMAKG--VKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVN
>hIA2beta_D1_(NP_002838)_PTPRN2 .
HMILSYMEDHLKNKN-------RLEKEWEALCAY-----QAEPNSSFVAQREENVPK-NR
SLAVLTYDHSRVLLKAENSH---------------------SHSDYINASPIMDHDPRNP
-------AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLAEN-GVRQCYHYWP----D
EGSNLYHIYEVNLVSEHIW-CEDFLVRSFYLKNLQT-----------NETRTVTQFHFLS
WYDRGVPSS--SRSLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRSGTY
VLIDMVLNKMAKG--AKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVN
>macneIA2beta_D1_(O02695) .
HMILSYMEDHLKNKN-------RLEKEWEALCAY-----QAEPNSSLVAQKEENVPK-NR
SLAVLTYDHSRVLLKAENSH---------------------SHSDYINASPIMDHDPRNP
-------AYIATQGPLPATVADFWQMVWESGCVVIVMLTPLTEN-GVRQCYHYWP----D
EGSNLYHIYEVNLVSEHIW-CEDFLVRSFYLKNLQT-----------NETRTVTQFHFLS
WYDRGVPSS--SRSLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRSGTY
VLIDMVLNKMAKG--AKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVN
>mPTPNP_D1_(P80560)_Ptprn2 .
HMILAYMEDHLKNKN-------RLEKEWEALCAY-----QAEPNSSLVAQREENAPK-NR
SLAVLTYDHSRILLKSQNSH---------------------GSSDYINASPIMDHDPRNP
-------AYIATQGPLPATVADFWQMVWESGCAVIVMLTPLSEN-GVRQCHHYWP----D
EGSNLYHVYEVNLVSEHIW-CQDFLVRSFYLKNLQT-----------NETRTVTQFHFLS
WYDQGVPSS--TRSLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRSGTY
VLIDMVLNKMAKG--AKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVN
>rPTPNE6_D1_(NP_113788)_Ptprn2 .
HMILAYMEDHLKNKN-------RLEKEWEALCAY-----QAEPDSSLVAQREENAPK-NR
SLAVLTYDHSRILLKSENSH---------------------SNSDYINASPIMDHDPRNP
-------AYIATQGPLPATVADFWQMVWESGCAVIVMLTPLSEN-GVRQCHHYWP----D
EGSNVYHVYEVNLVSEHIW-CQDFLVRSFYLKNLQT-----------NETRTVTQFHFLS
WYDQGVPSS--TRSLLDFRRKVNKCYR-------------GRSCPIIVHCSDGAGRSGTY
VLIDMVLNKMAKG--AKEIDIAATLEHLRDQRPGMVQTKEQFEFALTAVAEEVN
>hCD45_D2_(NP_002829)_PTPRC .
SELHPYLHNMKKRDPP--SEPSPLEAEFQRLP------SYRSWRTQHIGNQEENKSK-NR
NSNVIPYDYNRVPLKHELEMS--KESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPE-
-------VMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELKHG-DQEICAQYWGE----
-GKQTYGDIEVDLKDTDK--SSTYTLRVFELRHSKRK-----------DSRTVYQYQYTN
WSVEQLPAE--PKELISMIQVVKQKLPQKNSSEGN---KHHKSTPLLIHCRDGSQQTGIF
CALLNLLESAET---EEVVDIFQVVKALRKARPGMVSTFEQYQFLYDVIASTYP
>mCD45_D2_(NP_035340)_Ptprc .
SELHSCLHNMKKRDPP--SDPSPREAEYQRLP------SYRSWRTQHIGNQGENKKK-KR
NSNVVPYDFNRVPLKHELEMS--KESEPESDESSDDDSDSEETSKYINASFVMSYWKPE-
-------MMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELVNG-DQEVCAQYWGE----
-GKQTYGDMEVEMKDTNR--ASAYTLRTFELRHSKRK-----------EPRTVYQYQCTT
WKGEELPAE--PKDLVSMIQDLKQKLPKASPEGM----KYHKHASILVHCRDGSQQTGLF
CALFNLLESAET---EDVVDVFQVVKSLRKARPGVVCSYEQYQFLYDIIASIYP
>rCD45_D2_(XP_213985)_Ptprc .
SELHSCLQNLKKRDPP--SDPSPLEAEYQRLP------SYRSWRTQHIGNQEENKKK-NR
SSNVVPYDFNRVPLKHELEMS--KESEAESDESSDEDSDSEETSKYINASFVMSYWKPE-
-------MMIAAQGPLKETIGDFWQMIFQRKVKVIVMLTELMSG-DQEVCAQYWGE----
-GKQTYGDMEVMLKDTNK--SSAYILRAFELRHSKRK-----------EPRTVYQYQCTT
WKGEELPAE--PKDLVTLIQNIKQKLPKSGSEGM----KYHKHASILVHCRDGSQQTGLF
CALFNLLESAET---EDVVDVFQVVKSLRKARPGMVGSFEQYQFLYDIMASIYP
>cCD45_D2_(A54080) .
SELHSYLNNLKRKDPP--SEPSLLEAKFQRLP------SYKGWRTQNTGNREENKNK-NR
SANTIPYDFNRVPIRSEEEQS--KEGEHDSEDSSDEDSDCEESSRYINASFITGYWGPK-
-------AMIATQGPLQETISDFWQMVFQRKVKVIVMLTELKEG-DQELCAQYWGE----
-GRQTYDDIEVQVTDVNC--CPSYTIRAFDVTHLKRK-----------ETQKVYQYQYHK
WNGLDVPED--PKDLVDMILSLKQKVPSRPASEDS---RNSRSVPFVIHCCDGSQQTWCV
LCLMTLLESAET---EEVIDVFQVVKALRRSRLGVVSTFEQYQFLYDTIARTYP
>fuCD45_D2_(CAB96211) .
QELHSTLNTLKQRSSD--NEPTLLEDEFERLP------NFKNWRTFNTGVTEENKKK-NR
TSSVIPYDYNRVLLKLDEEKSHESDPDPDDDYDTSSYDDIEDSAKYINASLLSGYWGPH-
-------TFISAQTPLPDTVADFWSMILQKRVSIVVMLSDCSQG---DEDCVYWGE----
-DKKTVEDIEVETESTDN--SPNFILRNMMIHHLKTD-----------AHQQVKHFQFLK
WGDKEVPEK--PQDLADLIKEIKHRCGY----------TWPRSTPIIVHCNDGSSRSGAF
CALWNLLDNAEK---EKMVDVFQVVKTLRKERQGMCPSLEQYQFLYDALEVVYP
>cypcaCD45_D2_(BAA92179) .
SEFHSVLNTLRQKNG---SDPSLLEKEFQKLP------KFKKWRTMNTGSSEDNKKK-NR
DSAVIPYDFNRVIFRLDIEGN---QTSDPEDEEEYSSDEEEESNQYINASFIDGYWCNK-
-------SLIAAQGPLQSTAEEFLLMLYQQQTKTLVMLTDCQED-GKDYCFQYWGD----
-EKKTYGDMEIEVKKTET--FPTYVRRHLEIQSLKKK-----------EVLKVDQYQFLK
WRGRELPEN--AQELVEMASIIRENGHYDNS-------KTNRNVPIVVHCNNGSSRTGIF
CALWNLLDSAYT---EKLVDVLQEVKNLRKLRQGMVETIEQYQFLYTALEGAFP
>aotvoCD45_D2_(AAM48512)_(3') .
--------NMKKRDPP--SEPSPLEAEFQRLP------SYRSWRTQHIGNQEENKSK-NR
NSNVIPYDFNRVPLKHELEMS--KESEHDSDESSDDDSDSEEXSKYINASFIMXXWKPE-
-------VMIAAQGPLXETIGDFWQMIFQRKVKVIVMLTELKHG-DQEICAQYWGE----
-GKQTYGDIEVDLKDTDK--SSTYTLRVFELRHSKRK-----------DSRTVYQYQYTN
WSVXXLPAX--PKELISMIQVXKQKLPQKNSSEGN---KXHKSXPLLIHCRDGSQQTGIF
CALLNLLESAET---EEVVDXFQVVKALRKARPGMXSTFEQXQFLYDXIASTYP
>sharkCD45_D2_(T43148) .
SELPKHLINFKKNDPP--SEPSMLEGEFQRIP------PYTDWRTQTTGRRGENQSK-NR
SLSVIAYDYNRVTIKLEDEKS-KDSTSHSDSDLSSDDSEDEESTKYINASYIDGYWHSE-
-------TLIATQTPLPETIADFWMMVYQRKARIIAMLGKLKD---DKDCSQYWED----
-DKKTYDDIEVVLSECNK--QPEFIVRIFEIRHTKRK-----------ETRQVYQYHFHD
WAESELPED--PSNFTKMIRSIKEKLSTLQEPE------SSLSPSLIVHCSDGAKKTGVF
YALWILLDNADT---ENVIDVLQTVKVLRKARPGLVSTFEQYQFLYDIIASTYP
>cPTPalpha_D2_(AAB04150) .
TSLEIHLQKIYNKVP--GTSSNGLEEEFKKLTS-----IKIQNDKMRTGNLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDGYRRRT-
--------PTCQPRPVQHTIEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
DGSVSYGDINVELKKEEE--CESYTVRDLLVTNTREN-----------KSRQIRQFHFHG
WPEVGIPSD--GKGMINIIAAVQKQQQ------------QSGNHPMHCHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
>hPTPalpha_D2_(NP_002827)_PTPRA .
TSLETHLQKIYNKIP--GTSNNGLEEEFKKLTS-----IKIQNDKMRTGNLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDGYRQKD-
-------SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
DGLVSYGDITVELKKEEE--CESYTVRDLLVTNTREN-----------KSRQIRQFHFHG
WPEVGIPSD--GKGMISIIAAVQKQQQ------------QSGNHPITVHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
>mPTPalpha_D2_(NP_033006)_Ptpra .
TSLETHLQKIYNKIP--GTSNNGLEEEFKKLTS-----IKIQNDKMRTGNLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDGYRQKD-
-------SYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
DGLVSYGDITVELKKEEE--CESYTVRDLLVTNTREN-----------KSRQIRQFHFHG
WPEVGIPSD--GKGMINIIAAVQKQQQ------------QSGNHPITVHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
>rPTPalpha_D2_(NP_036895)_Ptpra .
TSLDTHLQKIYNKIP--GTSNNGLEEEFKKLTS-----IKIQNDKMRTGYLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDPYRQKD-
-------SYIASQGPLLHTTEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
DGLVSYGDITVELKKEEE--CESYTVRDLLVTNTREN-----------KSRQIRQFHFHG
WPEVGIPSD--GKGMINIIAAVQKQQQ------------QSGNHPITVHCSAGAGRTGTF
CALSTVLECVKA---EGILDVFQTVKTLRLQRPHMVQILEQYEFCYKVVQEYID
>xPTPalpha_D2_(AAA17990) .
TSLETHLQKLYSKFP--GTNSTGLEEEFKKLTS-----IKIQNDKMRTGNFPAYMKE-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDGYRQKD-
-------SYIAGQGPLRHSLEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
EGTMSFGDITIELKKEEE--SESYTVRDMFVTNTREN-----------KSRQIRQFHFHG
WPEVGIPTD--GKGMINIIAAVQKQQQ------------QSGNHPITVHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYRVVQEYID
>zPTPalpha_D2_(NP_571963)_ptpra .
TSLETHMNKLYAPLP--GAGCGGLEAEFKKLTS-----IKIQNDKMRTGNLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYINASFIDGYRQKD-
-------SYMACQGPLQHTIEDYWRMIWEWRSCSIVMLTELEER-GQEKCAQYWPT----
DGVMVCGDMSIELKREEE--SESYTVRDLLVTNNREN-----------KSRAVRQFHFHG
WPEVGIPSD--GKGMINIIAAVQKQQQ------------QSGNHPITSHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
>ryPTPR4b_D2_(BAA95196) .
TSLESHLQKLYNRVS--GSGCNGLEEEFKKLTS-----IKIQNDKMRTGNLPANMKK-NR
VLQIIPYEFNRVIIPVKRGE---------------------ENTDYVNASFIDGYRQKD-
-------SYIASQGPLQHTIEDFWRMIWEWKSCSIVMLTELEER-GQEKCAQYWPS----
EGTVTYGDITIEIKKEEE--SESYTVRDLLVTNTREN-----------KVRQIRQFHFHG
WPEVGIPAD--GKGMINLIAAVQKQQQ------------QSGNHPITVHCSAGAGRTGTF
CALSTVLERVKA---EGILDVFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID
>hPTPepsilon_D2_(NP_006495)_PTPRE .
SSLEKHLQTMHGTTT--HFDKIGLEEEFRKLTN-----VRIMKENMRTGNLPANMKK-AR
VIQIIPYDFNRVILSMKRGQ---------------------EYTDYINASFIDGYRQKD-
-------YFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQER-EQDKCYQYWPT----
EGSVTHGEITIEIKNDTL--SEAISIRDFLVTLNQPQARQE------EQVRVVRQFHFHG
WPEIGIPAE--GKGMIDLIAAVQKQQQ------------QTGNHPITVHCSAGAGRTGTF
IALSNILERVKA---EGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID
>mPTPepsilon_D2_(NP_035342)_Ptpre .
SSLERHLQTLHSTAT--HFDKIGLEEEFRKLTN-----VRIMKENMRTGNLPANMKK-AR
VIQIIPYDFNRVILSMKRGQ---------------------EFTDYINASFIDGYRQKD-
-------YFMATQGPLAHTGEDFWRMVWEWKSHTIVMLTEVQER-EQDKCYQYWPT----
EGSVTHGDITIEIKSDTL--SEAISVRDFLVTFKQPLARQE------EQVRMVRQFHFHG
WPEVGIPAE--GKGMIDLIAAVQKQQQ------------QTGNHPITVHCSAGAGRTGTF
IALSNILERVKA---EGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID
>rPTPepsilon_D2_(XP_215102)_Ptpre .
SSLERHLQTLHGTAT--HFDKIGLEEEFRKLTN-----VRIMKENMRTGNLPANMKK-AR
VIQIIPYDFNRVILSMKRGQ---------------------EFTDYINASFIDGYRQKD-
-------YFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQER-EQDKCYQYWPT----
EGSVTHGDITIEIKSDTL--SEAISIRDFLVTFKQPLARQE------EQVRMVRQFHFHG
WPEVGIPTE--GKGMIDLIAAVQKQQQ------------QTGNHPITVHCSAGAGRTGTF
IALSNILERVKA---EGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFID
>orylaPTPepsilon_D2_(BAC06424) .
CSLEGHLHRLHNTRA--PNDRLGLEEEFRKLTN-----VRIMKENMRTGNLPANMRK-NR
VLQIIPYDFNRVILSVRRGQ---------------------EFTDYINASFIDGYRQKD-
-------YFIATQGPLSHTVEDFWRMVWEWRCHSIVMLTELKER-EQEKCFQYWPS----
EGSVIFGDYAVELTGESQ--GETFTRKDMLLTYKSCLSQQE------KQPQHVRHFHFHG
WPEIGIPVD--GRGMIDIIAAVQRQQQ------------QSGNRPIIVHCSAGAGRTGTF
IALSNILERVKA---EGLLDVFQTVKSLRMQRPHMVQTVEQYDFCYKVVQDFID
>ryPTPR4a_D2_(BAA95190) .
SSLEKHIQKLRNKTG--KFDITGLEEEFNKLTT-----VRIRKDNMRTGNKPVNMKK-AR
VLQIIPYDFNRVVLPRKRGQ---------------------EFSDYINASYIDGYRQKD-
-------YFVATQGPLAHTVEDFWRMVWDCKSHTIVMLTELRER-EQEKCCQYWPS----
EGSVTYGTYSTELKKDNI--TDAFSLRDLTVTNTTEN-----------IERTVRQFHFHD
WPEIGIPAE--GKGMIDLIAAVQKQQQ------------KSGNHPIIVHCSAGAGRTGTF
IALSNILERVKA---EGLLDVFQTVKSLRMQRPHMVQTLEQYDFCYKVVQDFLD
>hPTPkappa_D2_(NP_002835)_PTPRK .
KAAYFDMIRIDSQTN-----SSHLKDEFQTLNS---VTPRLQAEDCSIACLPRNHDK-NR
FMDMLPPDRCLPFLITIDG----------------------ESSNYINAALMDSYRQPA-
-------AFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDL---SQGCPQYWPE----
EGMLRYGPIQVECMSCSM--DCDVINRIFRICNLTRPQ---------EGYLMVQQFQYLG
WASHREVPGS-KRSFLKLILQVEKWQEEC----------EEGEGRTIIHCLNGGGRSGMF
CAIGIVVEMVKR---QNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLE
>mPTPkappa_D2_(NP_033009)_Ptprk .
KAAYFDMIRIDSQTN-----SSHLKDEFQTLNS---VTPRLQAEDCSIACLPRNHDK-NR
FMDMLPPDRCLPFLITIDG----------------------ESSNYINAALMDSYRQPA-
-------AFIVTQYPLPNTVKDFWRLVYDYGCTSIVMLNEVDL---SQGCPQYWPE----
EGMLRYGPIQVECMSCSM--DCDVINRIFRICNLTRPQ---------EGYLMVQQFQYLG
WASHREVPGS-KRSFLKLILQVEKWQEEC----------EEGEGRTIIHCLNGGGRSGMF
CAIGIVVEMVKR---QNVVDVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYLE
>ryPTPR2B_D2_(BAA95194) .
KQAYYEMIRVDSQSN-----SSQLKDEFQTLNS---VSSQLQPEDCSIALLPRNHEK-NR
YMDALPPDRCLPFLITIDG----------------------ESSNYINAALMDSYRQPA-
-------AFIVTQHPLPNTVKDFWRLVYDYGCTSVVMLNELDL---VQGCPQYWPE----
EGTLRYGPIQVDCVSCSM--DCDLVSRLFRICNLTRPQ---------EGYLMVQQFQYLG
WAAHREIPAS-KRSFLKLILQVDKWQEEC----------EEGEGRTIIHCLNGGGRSGMF
CAITIICEMIKR---QNVVDIFHGVKTLRNSRPNMVETLDQYRFCYDVALEYLE
>hPTPlamda_D2_(NP_005695)_PTPRU .
KATYKEMIRIDPQSN-----SSQLREEFQTLNS---VTPPLDVEECSIALLPRNRDK-NR
SMDVLPPDRCLPFLISTDG----------------------DSNNYINAALTDSYTRSA-
-------AFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPE----
PGRQQYGLMEVEFMSGTA--DEDLVARVFRVQNISRLQ---------EGHLLVRHFQFLR
WSAYRDTPDS-KKAFLHLLAEVDKWQAES------------GDGRTIVHCLNGGGRSGTF
CACATVLEMIRC---HNLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE
>mPTPlamda_D2_(NP_035344)_Ptprl .
RATYREMIRIDPQSN-----SSQLREEFQTLNS---VTPPLDVEECSIALLPRNRDK-NR
SMDVLPPDRCLPFLISSDG----------------------DPNNYINAALTDSYTRSA-
-------AFIVTLHPLQSTTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWPE----
PGRQQYGLMEVEFVSGTA--NEDLVSRVFRVQNSSRLQ---------EGHLLVRHFQFLR
WSAYRDTPDS-RKAFLHLLAEVDKWQAES------------GDGRTVVHCLNGGGRSGTF
CACATVLEMIRC---HSLVDVFFAAKTLRNYKPNMVETMDQYHFCYDVALEYLE
>hPTPmu_D2_(NP_002836)_PTPRM .
RSLYYDMNKLDPQTN-----SSQIKEEFRTLNM---VTPTLRVEDCSIALLPRNHEK-NR
CMDILPPDRCLPFLITIDG----------------------ESSNYINAALMDSYKQPS-
-------AFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP---AQLCPQYWPE----
NGVHRHGPIQVEFVSADL--EEDIISRIFRIYNAARPQ---------DGYRMVQQFQFLG
WPMYRDTPVS-KRSFLKLIRQVDKWQEEYN----------GGEGPTVVHCLNGGGRSGTF
CAISIVCEMLRH---QRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN
>mPTPmu_D2_(NP_033010)_Ptprm .
RSLYYDMNKLDPQTN-----SSQIKEEFRTLNM---VTPTLRVEDCSIALLPRNHEK-NR
CMDILPPDRCLPFLITIDG----------------------ESSNYINAALMDSYKQPS-
-------AFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP---AQLCPQYWPE----
NGVHRHGPIQVEFVSADL--EEDIISRIFRIYNASRPQ---------DGHRMVQQFQFLG
WPMYRDTPVS-KRSFLKLIRQVDKWQEEYN----------GGEGPTVVHCLNGGGRSGTF
CAISIVCEMLRH---QRTVDVFHAVKTLRNNKPNMVDLLDQYKFCYEVALEYLN
>rPTPmu_D2_(XP_237546_(revised)) .
RSLYYDMNKLDPQTN-----SSQIKEEFRTLNM---VTPTLRVEDCSIALLPRNHEK-NR
CMDILPPDRCLPFLITIDG----------------------ESSNYINAALMDSYKQPS-
-------AFIVTQHPLPNTVKDFWRLVLDYHCTSVVMLNDVDP---TQLCPQYWPE----
NGVHRHGPIQVEFVSADL--EEDIISRIFRIYNASRPQ---------DGHRMVQQFQFLG
WPMYRDTPVS-KRSFLKLIRQVDKWQEEYN----------GGEGRTVVHCLNGGGRSGTF
CAISIVCEMLRH---QRTVDVFHAVKTLRNNKPNMVDLLQSWSSRETRALVLSS
>hPTPrho_D2_(NP_573400)_PTPRT .
RSLYYNISRLDPQTN-----SSQIKDEFQTLNI---VTPRVRPEDCSIGLLPRNHDK-NR
SMDVLPLDRCLPFLISVDG----------------------ESSNYINAALMDSHKQPA-
-------AFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDT---AQFCMQYWPE----
KTSGCYGPIQVEFVSADI--DEDIIHRIFRICNMARPQ---------DGYRIVQHLQYIG
WPAYRDTPPS-KRSLLKVVRRLEKWQEQYD----------GREGRTVVHCLNGGGRSGTF
CAICSVCEMIQQ---QNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLS
>mPTPrho_D2_(NP_067439)_Ptprt .
RSLYYNISRLDPQTN-----SSQIKDEFQTLNI---VTPRVRPEDCSIGLLPRNHDK-NR
SMDVLPLDRCLPFLISVDG----------------------ESSNYINAALMDSHKQPA-
-------AFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDT---AQLCMQYWPE----
KTSGCYGPIQVEFVSADI--DEDIIHRIFRICNMARPQ---------DGYRIVQHLQYIG
WPAYRDTPPS-KRSLLKVVRRLEKWQEQYD----------GREGRTVVHCLNGGGRSGTF
CAICSVCEMIQQ---QNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLS
>cPTPsigma_D2_(I50212) .
RNLYTYIQKLAQIEVG--EHVTGMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYETTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQP-AMVQTEDEYQFCYQAALEYLG
>hLAR_D2_(NP_002831)_PTPRF .
RNLYAHIQKLGQVPPG--ESVTAMELEFKLLAS-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYELTRVCLQPIRG---------------------VEGSDYINASFLDGYRQQK-
-------AYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTIRQFQFTD
WPEQGVPKT--GEGFIDFIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>mLAR_D2_(NP_035343)_Ptprf .
RNLYAHIQKLGQVPPG--ESVTAMELEFKLLAN-----SKAHTSRFVSANLPCNKFK-NR
LVNIMPYELTRVCLQPIRG---------------------VEGSDYINASFLDGYRQQK-
-------AYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTIRQFQFTD
WPEQGVPKT--GEGFIDXIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>rLAR_D2_(NP_062122)_Ptprf .
RNLYAHIQKLGQVPPG--ESVTAMELEFKLLAG-----SKARASRFISANLPCNKFK-NR
LVNIMPYELTRVCLQPIRG---------------------VEGSDYINASFLDGYRQQK-
-------AYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTIRQFQFTD
WPEQGVPKT--GEGFIDFIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>xLAR_D2_(AAF43606) .
RSLYAHIQKLSQVPPG--ESVTSMELEFKLLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYELSRVSLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------GYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTIRQFQFTD
WPEQGVPKT--GEGFIDFIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>zLAR_D2_(CAC44758) .
RSLYTHIQKLTQAPPG--DTVTAMELEFKKLAN-----SKAHTSRFISASLPCNKFK-NR
LVNIMPFESSRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLSETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTIRQFQFTD
WPEQGVPKT--GEGFIDFIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTIKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>ryPTPR2Aa_D2_(BAA95188) .
RSLFAHIQKLGQVPPA--ETVTAMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYESTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYS--MPQYILREFKVTDARDG-----------QSRTIRQFHFID
WPEQGVPKT--GEGFIDFIGQVHKTKEQFG-----------QDGPITVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLG
>hPTPdelta_D2_(NP_002830)_PTPRD .
RNLYAYIQKLTQIETG--ENVTGMELEFKRLAS-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYESTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLG
>mPTPdelta_D2_(D54689) .
RNLYAYIQKLTQIETG--ENVTGMELEFKRLAS-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYESGRVCLQPIRG---------------------VEGSDYINASFLDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARD------------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLG
>xPTPdelta_D2_(AAF43605) .
RNLYAYIQKLTQIEPG--ENVTGMELEFKRLAS-----FKAHTSRFISANLPCNKFK-NR
LVNIMPYESTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLG
>ryPTPR2Ab_D2_(BAA95191) .
RNLYAYIQKLTQVEPG--ENVTGMELEFKRLAN-----TKAHTSRFISANLPCNKFK-NR
LVNIMPYESTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAALEYLG
>hPTPsigma_D2_(NP_002841)_PTPRS .
RSLYAYIQKLAQVEPG--EHVTGMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYESTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG
>mPTPsigma_D2_(NP_035348)_Ptprs .
RSLYTYIQKLAQVEPG--EHVTGMELEFKRLAS-----SKAHTSRFITASLPCNKFK-NR
LVNILPYESSRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGAPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLG
>xPTPsigma_D2_(AAF43607) .
RNLYTYIQNLAQIDVG--EHVIGMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYETTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG
>zPTPsigma_D2_(CAC44759) .
RSLFSYIQKLAQVEAG--EHVSGMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYETTRVCLQPIRG---------------------LEGSDYINSSFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG
>rPTPsigma_D2_(NP_062013)_Ptprd .
RSLYTYIQKLAQVEPG--EHVTGMELEFKRLAS-----SKAHTSRFITASLPCNKFK-NR
LVNILPYESSRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGAPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLG
>ryPTPR2Ac_D2_(BAA95193) .
RNLYSYIQKLTQVETG--EHVTGMELEFKRLAN-----SKAHTSRFISANLPCNKFK-NR
LVNIMPYETTRVCLQPIRG---------------------VEGSDYINASFIDGYRQQK-
-------AYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMG-REKCHQYWP----A
ERSARYQYFVVDPMAEYN--MPQYILREFKVTDARDG-----------QSRTVRQFQFTD
WPEQGVPKS--GEGFIDFIGQVHKTKEQFG-----------QDGPISVHCSAGVGRTGVF
ITLSIVLERMRY---EGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLG
>hPTPgamma_D2_(NP_002832)_PTPRG .
NQLHSYVNSILIPGVG---GKTRLEKQFKLVTQ-----CNAKYVECFSAQKECNKEK-NR
NSSVVPSERARVGLAPLPG---------------------MKGTDYINASYIMGYYRSN-
-------EFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQS--LAEDEFVYWPSREES
MNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDD-----------YVLEVRHFQCPK
WPNPDAPIS----STFELINVIKEEALT-------------RDGPTIVHDEYGAVSAGML
CALTTLSQQLEN---ENAVDVFQVAKMINLMRPGVFTDIEQYQFIYKARLSLVS
>mPTPgamma_D2_(NP_033007)_Ptprg .
SQLHSYVNSILIPGVG---GKTRLEKQFKLITQ-----CNAKYVECFSAQKECNKEK-NR
NSSVVPAERARVGLAPLPG---------------------MKGTDYINASYIMGYYRSN-
-------EFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQS--LAEDEFVYWPSREES
MNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDD-----------YVLEVRHFQCPK
WPNPDAPIS----STFELINVIKEEALT-------------RDGPTIVHDEYGAVSAGML
CALTTLSQQLEN---ENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLIS
>rPTPgamma_D2_(NP_599183)_Ptprg .
SQLHSYVNSILIPGVG---GKTRLEKQFKLITQ-----CNAKYVECFSAQKECNKEK-NR
NSSVVPAERARVGLAPLPG---------------------MKGTDYINASYIMGYYRSN-
-------EFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQS--LAEDEFVYWPSREES
MNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDD-------------------YVLE
VRHFQAPIS----STFELINVIKEEALA-------------RDGPTIVHDEYGAVSAGML
CALTTLSQQLEN---ENAVDVFQVAKMINLMRPGVFTDIEQYQFVYKAMLSLVS
>ryPTPR5b_D2_(BAA95197) .
SQLHGYVNSILIPGLS---GKMRLEKQFKLVTQ-----CNAKFIECFSAQKECNKEK-NR
NSSVVPTERARVGLAPLPG---------------------TKGTDYINASYIMGYYRSN-
-------EFIITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNHG--LAEDESVYWPSREES
MNCEAFTVTLISKDILCLSNEEQVIIHDFILEATQDD-----------YVLEVRHFQCPK
WPNPDAPLS----STFELINVLKEEAST-------------RDGPTIVHDEFGGVSAGLF
CGLTTLSQQLEC---ESAVDVYQVAKMINLMRPGVFTDIEQYQFLYKAMLSLIS
>cPTPgamma_D2_(Q98936) .
NQLHSYVNSILIPGIG---GKTRLEKQFKLVTQ-----CNAKYVECFSAQKDCNKEK-NR
NSSVVPSERARVGLAPLPG---------------------MKGTDYINASYIMGYYRSN-
-------ENVITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQS--LAEDEFVYWPSREES
MNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDD-----------YVLEVRHFQCPK
WPNPDAPIS----STFELINVIKEEALT-------------RDGPTIVHDEYGAVSAGTL
CALTTLSQQLEN---ENAVDVFQVAKMINLMRPGVFTDIEQYQFLYKAMLSLVS
>hPTPzeta_D2_(NP_002842)_PTPRZ1 .
SHIHAYVNALLIPGPA---GKTKLEKQFQLLSQ-----SNIQQSDYSAALKQCNREK-NR
TSSIIPVERSRVGISSLSG----------------------EGTDYINASYIMGYYQSN-
-------EFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQN--MAEDEFVYWPNKDEP
INCESFKVTLMAEEHKCLSNEEKLIIQDFILEATQDD-----------YVLEVRHFQCPK
WPNPDSPIS----KTFELISVIKEEAAN-------------RDGPMIVHDEHGGVTAGTF
CALTTLMHQLEK---ENSVDVYQVAKMINLMRPGVFADIEQYQFLYKVILSLVS
>cPTPzeta_D2_(AAA49015) .
THIHAYVNALLIPGPT---GKTRLEKQFKLLSQ-----SNTQQCDYSTALKQCNREK-NR
TSSIIPVERSRVGISSLSG----------------------EGTDYINASYIMGYYQSN-
-------EFIITQHPLLHTIKDFWRMIWDHNAQLIVMLPDSQN--MAEDEFVYWPNKDEP
INCETFKVTMIAEEHKCLSKEEKLIIQDFILEATQDD-----------YVLEVRHFQCPK
WPNPDSPIS----KTFELISIIKEETSN-------------RDGPMIVHDEHGGVTAGTF
CALTTLMHQLEN---ENSVDVYQVAKMINLMRPGVFTDIEQYQFLYKAILSLVS
>mPTPzeta_D2_(XP_133009)_Ptprz1 .
SHIHSYVNTLLIPGPT---GKTKLEKQFQLLSQ-----SNILQSDYSTALKQCNREK-NR
TSSIIPVERSRVGISSLSG----------------------EGTDYINASYIMGYYQSN-
-------EFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQN--MAEDEFVYWPNKDEP
INCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDD-----------YVLEVRHFQCPK
WPNPDSPIS----KTFELISIIKEEAAN-------------RDGPMIVHDEHGGVTAGTF
CALTTLMHQLEK---ENAMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVS
>rPTPzeta_D2_(NP_037212)_Ptprz1 .
SHIHSYVNTLLIPGPS---GKTKLEKQFQLLSQ-----SNILQSDYSTALKQCNREK-NR
TSSIIPVERSRVGISSLSG----------------------EGTDYINASYIMGYYQSN-
-------EFIITQHPLLHTIKDFWRMIWDHNAQLVVMIPDGQN--MAEDEFVYWPNKDEP
INCESFKVTLMSEEHKCLSNEEKLIVQDFILEATQDD-----------YVLEVRHFQCPK
WPNPDSPIS----KTFELISIIKEEAAN-------------RDGPMIVHDEHGGVTAGTF
CALTTLMHQLEK---ENSMDVYQVAKMINLMRPGVFTDIEQYQFLYKVVLSLVS
>xPTPzeta_D2_(BAA97445) .
THIHGYVNTLLTMGPS---GKSRLETQFKLLSE-----PNILQCDYSTALKPQNRDK-NR
TSSVIPVERSRVGLSSLAG----------------------EGTDYINASYVMGYHESN-
-------QFIITQHPLLHTIKDFWRMMWDHNSQLIVMLPDMQN--MAEDEFVYWPNKDQP
IVCDTFTVTLVREDHVCLSNEENLIIQDFILEATQDD-----------YVLEVRHFQCPK
WPNPDSPIS----KTFELINLIKEEAAN-------------KDGTIIVHDEYGGVTAGTF
CALYSLMHQLEQ---ENSLDVYQVVKMINLMRPGIFTDIEQYQFLYKAMLSLVS
>ryPTPR5a_D2_(BAA95195) .
NHLHTYVNALLTPGPS---GKTKLEKQFKLVSQ-----PHAKQCDYSAALKQCNRDK-NR
NSSIIPVERSRVGLATLTA----------------------EGSDYINASYVSGFHRID-
-------EFIVTQHPLPYTTKDFWRMIWDYNAQIIVMLPDNQG------LTPYWPKKDGP
MNYEAFTVSLLNESHLCLSNEEQLTIKDFILEATQDD-----------YVLEVRHYQSPR
WPNPDGPIS----KTFELLNLIRDAAAT-------------RDGPIIVHDEHGGITAGTF
CALTKLMDQLES---ENSVDVYQVAKMINLMRPGIFTDIDQFQFLYKAILSLVN