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Exon Structure of PTP Domains
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Click on an image to open and view the corresponding file (requires
either Microsoft Excel or the free Adobe
Acrobat Reader)
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Schematic representation of the exon structure of human PTP domains
PTP amino acid sequences are aligned to visualize the conservation of exon-intron boundaries within the gene family
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Excel Format
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Detailed version of PTP exon alignment including analysis of domains D2 from tandem domain RPTPs
Amino acids encoded by split codons, such as the invariant serine in the PTP signature motif ‘HCSxGxGR(S/T)’, are shown in italics
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Excel Format
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Mapping of exon structure onto the tertiary fold of PTP domains
Each individual color represents protein sequence encoded by a single exon.
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These images can be viewed dynamically by running the PyMOL molecular
graphics files below:
(To get PyMOL, see our download section)
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