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ConSurf analysis suggests unique functions for PTP domains D1 and D2 and
identifies conserved residues at the interface To map conservation scores
onto protein structure, we submitted to the ConSurf server a ClustalW alignment of
63 full-length tandem domain (D1D2) sequences and the X-ray
crystal structure of LAR (PDB identifier: 1LAR). The output file from the server
was colored according to its ConSurf scores (i.e. the b-values in the pdb file)
using PyMol and the ‘color_b.py’ script (histogram mode).
PDF
Format |
Powerpoint
Format
Fig. 6 | Fig. 6A | Fig. 6B |
Fig. 6C
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Fig.
6D
We provide the session files of the analysis for simple viewing on a PC or
Mac (requires PyMol installation). For comparison, the scores are colored in
ramp mode (see the
color_b.py script for details).
Fig. 6A | Fig. 6B |
Fig. 6C
Also we provide a Zip
file of the script used to generate Figure 6A-C (Methods
2005).
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